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- Title
Synthesis and characterization of chitosan ethers: Hydroxypropyl chitosan and Hydroxyethyl chitosan.
- Authors
Çelikçi, Nuran; Zıba, Cengiz Ayhan; Dolaz, Mustafa; Tümer, Mehmet
- Abstract
The hydroxypropyl chitosan (HPCH) and hydroxyethyl chitosan (HECH) are multifunctional chitosan derivatives with biocompatible and biodegradable properties. Due to their hydroxypropyl and hydroxethyl groups, they have water solubility, moisture retention, and gelling properties. In this study, the chitosan derivatives HPCH and HECH were obtained in two steps alkalisation and etherification. For alkalisation, chitosan was kept in an alkaline medium at -18C for 7 days. For etherification; the reaction was carried out for 48 hours by mixing alkaline chitosan with propylene oxide and ethylene oxide separately in a pressure reactor. The structures of the obtained HPCH and HECH were characterised by FT-IR, 1H(13C)-NMR, XRD, and TG analysis methods. Since the degree of deacetylation (DA) of chitosan is 75-85%, the chitosan units contain N-acetyl (-N-(CO)-CH3)) groups in addition to NH2 functional groups. When the 1H(13C)-NMR spectrum of chitosan was examined, the peak value of these acetyl groups was observed at δ1.89 ppm. When the XRD spectra were examined, it was observed that the strong peak in chitosan at 2θ-20° was weakened in HPCH and HECH. In addition, the thermal stability of HPCH and HECH was found to be higher than chitosan in TG analysis.
- Subjects
CHITOSAN; ETHYLENE oxide; PROPYLENE oxide; ETHERS; ACETYL group; X-ray diffraction
- Publication
Manas Journal of Engineering, 2024, Vol 12, Issue 1, p145
- ISSN
1694-7398
- Publication type
Article
- DOI
10.51354/mjen.1477354