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- Title
火麻仁油藻油组合物辅助降血脂功能 人体试食试验.
- Authors
陈则华; 李泓颖; 周勇; 李文治
- Abstract
Objective: To study the effect of hemp seed and algal oil mixture in lowering blood lipids, and provide the theoretical basis for the utilization of hemp seed and algal oil mixture in food. Methods: 113 hyperlipidemia adult volunteers were selected and randomly divided into two groups, namely the experiment group and the control group. The subjects in the experiment group were given gelatinized confections for 90 dayst while subjects in the control group were given a placebo. The levels of Serum total cholesterol(TC), Triglyceride (TG), Iligh-density lipoprotein cholesteroK IIDL-C) t Low-density lipoprotein cholesterol (LDL-C) and physiological and biochemical parameters were measured before and alter trial. For the experiment group, hepatobiliary ultra sonograph carotid plaque ultrasonography fasting blood glucose, glycosylated hemoglobin, inllammatory indicators tumor necrosis lactor-a, interleukin-6, C-reactive protein and antioxidant indicators superoxide dismutase, malondialdehyde, glutathione peroxidase were detected. Results: Al the end of the human trial, compared with the control group, serum TC, TG and LDL-C levels of the experiment group decreased significantly (P < 0.05). And the rate of ellective lowering lipid level is 30.4% in the experiment group at the end of trials. No abnormal effect was observed in liver (unciion, renal function and hematological examination. In the experiment group, the levels of hBAlc and IL-6 were decreased (PV0.05), SOD and GSII-Px activities increased (P<0.01), the improvement rate of carotid plaque and laity liver was 33.3% and 39.3%, respectively. Conclusion: Ilemp seed and algal oil mixture tested in the study have a good lunction of lowering blood lipid in humans with an acceptable safety profile, which may be related to anti-innammatory and antioxidant ellects.
- Subjects
LDL cholesterol; CAROTID artery ultrasonography; BLOOD lipids; BLOOD cholesterol; CONTROL groups; GLUTATHIONE peroxidase
- Publication
Food & Machinery, 2023, Issue 8, p147
- ISSN
1003-5788
- Publication type
Article
- DOI
10.13652/j.spjx.1003.5788.2023.60028