We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Theta Rhythmopathy as a Cause of Cognitive Disability in TLE.
- Authors
Shuman, Tristan; Amendolara, Benjamin; Golshani, Peyman
- Abstract
Memory difficulties are commonly associated with temporal lobe epilepsy (TLE) and cause significant disability. This article reviews the role of altered hippocampal theta oscillations and theta-gamma coupling as potential causes of memory disturbance in temporal lobe epilepsy, dissecting the potential mechanisms underlying these changes in large-scale neuronal synchronization. We discuss development of treatments for cognitive dysfunction directed at restoring theta rhythmicity and future directions for research.
- Subjects
COGNITION disorders treatment; THETA rhythm; TEMPORAL lobe epilepsy; SYNCHRONIZATION; OSCILLATIONS
- Publication
Epilepsy Currents, 2017, Vol 17, Issue 2, p107
- ISSN
1535-7597
- Publication type
Article
- DOI
10.5698/1535-7511.17.2.107