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- Title
Effect of High-Intensity Interval Training on Visceral and Liver Fat in Cardiac Rehabilitation: A Randomized Controlled Trial.
- Authors
Taylor, Jenna L.; Holland, David J.; Mielke, Gregore I.; Bailey, Tom G.; Johnson, Nathan A.; Leveritt, Michael D.; Gomersall, Sjaan R.; Rowlands, Alex V.; Coombes, Jeff S.; Keating, Shelley E.
- Abstract
<bold>Objective: </bold>This study aimed to investigate the effect of exercise intensity on visceral adipose tissue (VAT) and liver fat reduction in patients with coronary artery disease (CAD) over 3 months and the maintenance of improvements over 12 months.<bold>Methods: </bold>Forty-two participants with CAD were randomized to three sessions/week of either 4 × 4-minute high-intensity interval training (HIIT) or 40 minutes of usual care moderate-intensity continuous training (MICT) for a 4-week supervised cardiac rehabilitation program, followed by three home-based sessions/week for 11 months. Liver fat (as intrahepatic lipid) and VAT were measured via magnetic resonance techniques. Data are mean change (95% CI).<bold>Results: </bold>HIIT and MICT significantly reduced VAT over 3 months (-350 [-548 to -153] cm3 vs. -456 [-634 to -278] cm3 ; time × group effect: P = 0.421), with further improvement over 12 months (-545 [-818 to -271] cm3 vs. -521 [-784 to -258] cm3 ; time × group effect: P = 0.577) and no differences between groups. Both groups improved liver fat over 3 months, with HIIT tending to show greater reduction than MICT (-2.8% [-4.0% to -1.6%] vs. -1.4% [-2.4% to -0.4%]; time × group effect: P = 0.077). After 12 months, improvements were maintained to a similar degree. Higher exercise intensity predicted liver fat reduction (β = -0.3 [-0.7 to 0.0]; P = 0.042).<bold>Conclusions: </bold>HIIT and MICT reduced VAT over 3 and 12 months. For liver fat, HIIT tended to provide a slightly greater reduction compared with MICT. These findings support HIIT as a beneficial adjunct or alternative to MICT for reducing visceral and liver fat in patients with CAD.
- Subjects
HIGH-intensity interval training; CARDIAC rehabilitation; RANDOMIZED controlled trials; FAT; LIVER; ADIPOSE tissue physiology; BODY composition; RESEARCH; RESEARCH methodology; SELF-evaluation; EVALUATION research; MEDICAL cooperation; TREATMENT effectiveness; COMPARATIVE studies; CORONARY artery disease; RESEARCH funding; PATIENT compliance; STATISTICAL sampling; ADIPOSE tissues; HEALTH self-care
- Publication
Obesity (19307381), 2020, Vol 28, Issue 7, p1245
- ISSN
1930-7381
- Publication type
journal article
- DOI
10.1002/oby.22833