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- Title
Large-Volume Injection LC-MS-MS Methods for Aqueous Samples and Organic Extracts.
- Authors
Allred, B. McKay; Perkins, Matthew J.; Field, Jennifer A.
- Abstract
Environmental sample analysis by large-volume injection (LVI) in combination with liquid chromatography-tandem mass spectrometry (LC-MS-MS) is described for polar and nonpolar analytes in both aqueous samples and organic extracts. LVI is the direct introduction of large sample volumes (for example, 900-1800 μL) into the LC system for separation and subsequent detection. The practical benefits of LVI include faster sample preparation times, lower detection limits, and minimal waste generation.
- Subjects
ANALYTICAL chemistry; AQUEOUS solutions; EXTRACTION (Chemistry); ORGANIC compounds; LIQUID chromatography-mass spectrometry; ENVIRONMENTAL sampling
- Publication
LC-GC Europe, 2015, Vol 28, Issue 5, p265
- ISSN
1471-6577
- Publication type
Article