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- Title
Outcome of Critically Ill Patients with Testicular Cancer.
- Authors
Ñamendys-Silva, Silvio A.; Barragán-Dessavre, Mireya; Bautista-Ocampo, Andoreni R.; García-Guillén, Francisco J.; Córdova-Sánchez, Bertha M.; Constantino-Hérnandez, Edgar; Correa-García, Paulina; González-Chon, Octavio; Herrera-Gómez, Angel
- Abstract
Purpose. To evaluate the clinical characteristics and outcomes of critically ill patients with testicular cancer (TC) admitted to an oncological intensive care unit (ICU). Methods. This was a prospective observational study. There were no interventions. Results. During the study period, 1,402 patients with TC were admitted to the Department of Oncology, and 60 patients (4.3%) were admitted to the ICU. The most common histologic type was nonseminomatous germ cell tumors (55/91.7%). The ICU, hospital, and 6-month mortality rates were 38.3%, 45%, and 63.3%, respectively. The Cox multivariate analysis identified the white blood cells count (HR = 1.06, 95% CI = 1.01–1.11, and P=0.005), ionized calcium (iCa) level (HR = 1.23, 95% CI = 1.01–1.50, and P=0.037), and 2 or more organ failures during the first 24 hours after ICU admission (HR = 3.86, 95% CI = 1.96–7.59, and P<0.001) as independent predictors of death for up to 6 months. Conclusion. The ICU, hospital, and 6-month mortality rates were 38.3%, 45%, and 63.3%, respectively. The factors associated with an increased 6-month mortality rate were white blood cells count, iCa level, and 2 or more organ failures during the first 24 hours after ICU admission.
- Subjects
CATASTROPHIC illness; TESTIS tumors; TREATMENT effectiveness; LONGITUDINAL method; SCIENTIFIC observation; TERMINALLY ill; DIAGNOSIS; TUMOR treatment
- Publication
BioMed Research International, 2017, Vol 2017, p1
- ISSN
2314-6133
- Publication type
Article
- DOI
10.1155/2017/3702605