We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A + AVD for Treatment of Hodgkin Lymphoma Variant of Richter's Transformation.
- Authors
Heyman, Benjamin; Choi, Michael; Kipps, Thomas J.
- Abstract
Hodgkin lymphoma variant of Richter's transformation (HvRT) is a rare complication for patients with chronic lymphocytic leukemia (CLL), with an overall poor prognosis. We present the first known case series of patients with HvRT treated with the combination of brentuximab vedotin, doxorubicin, vinblastine, and dacarbazine (A + AVD). In our series of 4 patients, two patients treated with A + AVD for HvRT had durable remissions of 40 and 42 months, while two patients had disease progression and ultimately died. Continued investigation into the optimal management for patients with HvRT is still needed.
- Subjects
RICHTER syndrome; HODGKIN'S disease; CHRONIC lymphocytic leukemia; CANCER treatment
- Publication
Case Reports in Hematology, 2024, Vol 2024, p1
- ISSN
2090-6560
- Publication type
Case Study
- DOI
10.1155/2024/7612622