We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Target-controlled infusion of propofol for a patient with myotonic dystrophy.
- Authors
Morimoto, Yasuhiro; Mii, Masako; Hirata, Takao; Matayoshi, Hiroaki; Sakabe, Takefumi
- Abstract
We present a patient with myotonic dystrophy (MD) who was anesthetized with propofol using a target-controlled technique for electrophysiologic examination and cardiac catheter ablation. The patient became apneic unexpectedly at the same time when he fell asleep, with effect-site propofol concentration of 1.6 µg ml−1. We had to insert a laryngeal mask airway (LMA), and mechanical ventilation was performed. The patient opened his eyes on verbal command at an effect-site concentration of 1.2 µg ml−1 after the procedure. This concentration (1.2 µg ml−1) was slightly lower than our institutional average for adult male patients (1.5 ± 0.2 µg ml−1). However, the time from the end of anesthesia to the patient's awakening was about 10 min. We considered that emergence from anesthesia was not delayed in this case. Careful titration of propofol by target-controlled infusion (TCI) enabled to evaluate the patient's sensitivity to propofol. We conclude that TCI of propofol was a useful anesthetic technique in the MD patient. Respiratory depression might occur in MD patients at low propofol concentrations. Precise control and titration over target propofol concentration is important in anesthetic management for MD patients.
- Subjects
MYOTONIA atrophica; ANESTHESIA; CATHETER ablation; CATHETERIZATION; PATIENTS
- Publication
Journal of Anesthesia, 2005, Vol 19, Issue 4, p336
- ISSN
0913-8668
- Publication type
Article
- DOI
10.1007/s00540-005-0348-7