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- Title
Advancement in Paper-Based Electrochemical Biosensing and Emerging Diagnostic Methods.
- Authors
Benjamin, Stephen Rathinaraj; de Lima, Fábio; Nascimento, Valter Aragão do; de Andrade, Geanne Matos; Oriá, Reinaldo Barreto
- Abstract
The utilization of electrochemical detection techniques in paper-based analytical devices (PADs) has revolutionized point-of-care (POC) testing, enabling the precise and discerning measurement of a diverse array of (bio)chemical analytes. The application of electrochemical sensing and paper as a suitable substrate for point-of-care testing platforms has led to the emergence of electrochemical paper-based analytical devices (ePADs). The inherent advantages of these modified paper-based analytical devices have gained significant recognition in the POC field. In response, electrochemical biosensors assembled from paper-based materials have shown great promise for enhancing sensitivity and improving their range of use. In addition, paper-based platforms have numerous advantageous characteristics, including the self-sufficient conveyance of liquids, reduced resistance, minimal fabrication cost, and environmental friendliness. This study seeks to provide a concise summary of the present state and uses of ePADs with insightful commentary on their practicality in the field. Future developments in ePADs biosensors include developing novel paper-based systems, improving system performance with a novel biocatalyst, and combining the biosensor system with other cutting-edge tools such as machine learning and 3D printing.
- Subjects
THREE-dimensional printing; POINT-of-care testing; MACHINE learning; MACHINE tools; BIOSENSORS; MACHINE theory
- Publication
Biosensors (2079-6374), 2023, Vol 13, Issue 7, p689
- ISSN
2079-6374
- Publication type
Article
- DOI
10.3390/bios13070689