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- Title
Studies on the Mechanism of Hypoproteinemia in Gastric Cancer.
- Authors
YAMAOKA, KATSUHIKO; NOGUCHI, SADAO; HIGASHI, HIROMU; JINNAI, DENNOSUKE
- Abstract
The leakage of serum albumin into the gastric juice was measured using 131I-RISA as a tracer in 30 cases with — and eight cases without — gastric carcinoma. A marked increase of albumin leakage was noticed in six cases with gastric cancer. Apparent correlation was not found between the degree of leakage of serum albumin and any such factors as age, sex, gastric acidity, PAS stainability, Borrmann's type, histological type and size of crater.Edema of mucosa and submucosal tissue and severe lymphatic invasion of cancer cells were found in the cases with high leakage. These findings, therefore, suggested that stasis of lymph in the tumor and the surrounding normal tissue of the stomach was one of the causes of albumin leakage into the lumen of the stomach.
- Publication
Japanese Journal of Clinical Oncology, 1974, Vol 4, Issue 2, p97
- ISSN
0368-2811
- Publication type
Article