We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Neonatal Vitamin D Levels in Relation to Risk of Overweight at 7 Years in the Danish D-Tect Case-Cohort Study.
- Authors
Jensen, Camilla B.; Lundqvist, Marika; Sørensen, Thorkild I.a.; Heitmann, Berit L.
- Abstract
Background: Vitamin D level in pregnancy may be associated with risk of overweight in the offspring later in life. Methods: In a case-cohort study based on Danish biobanks and registers we examined the association between 25-hydroxy-vitamin D (25(OH)D) level at birth and overweight at 7 years. Cases of overweight (n = 871) were randomly selected among 7-yearold children from the Copenhagen School Health Records Register (CSHRR) with a BMI above the 90th percentile. The cohort (n = 1,311) was a random sample selected among all Danish children born during the same period. Neonatal 25(OH)D was measured in dried blood spots. Results: 25(OH)D 3 exhibited the expected seasonal variation. Median level of 25(OH)D 3 was 20.6 (11.9-33.3) nmol/l in the overweight group and 23.4 (13.5-34.3) nmol/l in the cohort. We found no association between neonatal 25(OH)D 3 level and risk of overweight at age 7 years, neither in the crude model (OR (CI) 1.00 (0.99; 1.00)) nor in a model adjusted for maternal ethnicity, educational level, civil status, parity, season and year of birth, and offspring ponderal index (OR (CI) 1.00 (0.99; 1.01)). Conclusion: Risk of overweight at 7 years of age was not associated with vitamin D level at birth.
- Subjects
VITAMIN D deficiency; VITAMIN deficiency; VITAMIN D in the body; DRIED blood spot testing; HYDROXYAPATITE synthesis; OVERWEIGHT children; WEIGHT gain risk factors; THERAPEUTICS
- Publication
Obesity Facts: The European Journal of Obesity, 2017, Vol 10, Issue 3, p273
- ISSN
1662-4025
- Publication type
Article
- DOI
10.1159/000471881