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- Title
A putative sodium-dependent inorganic phosphate co-transporter from Drosophila melanogaster.
- Authors
MacIver, Bryce; McCahill, Angela; Pathirana, Stephen; Leaper, Kevin; Bownes, Mary
- Abstract
We have isolated and sequenced a cDNA encoding a predicted 524 amino acid protein from a Drosophilamelanogaster ovarian library. Sequence comparisons suggest that this protein encodes a sodium-dependent inorganic phosphate co-transporter similar to a sequence isolated from a rat brain library. In situ hybridisation to messenger RNA in ovaries shows strong expression in germarium at stage 2 of oogenesis. Expression is then weak in follicle cells until stage 10, when high transcript levels are seen in the nurse cells and transferred to the oocyte. This presumably reflects functions in oogenesis and the production of stored mRNAs for use in embryogenesis.
- Subjects
DROSOPHILA melanogaster; ANTISENSE DNA; AMINO acids; RATS; EMBRYOLOGY; MESSENGER RNA
- Publication
Development Genes & Evolution, 2000, Vol 210, Issue 4, p207
- ISSN
0949-944X
- Publication type
Article
- DOI
10.1007/s004270050305