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- Title
Acetoxybenzoylglycylglycines as Potential Cerebroprotective Compounds.
- Authors
Brel’, A. K.; Tyurenkov, I. N.; Lisina, S. V.; Popov, S. S.; Verkholyak, D. V.; Budaeva, Yu. N.; Volotova, E. V.; Atapina, N. V.; Kurkin, D. V.
- Abstract
3,4,5-Trimethoxy- and 2-, 3-, and 4-acetoxybenzoylglycylglycines and their water-soluble potassium and lithium salts were synthesized. The cerebroprotective properties of the water-soluble potassium and lithium salts of acetoxybenzoylglycylglycines were studied experimentally. The most marked cerebroprotective proteins in cerebral ischemia were found with the lithium salt of 2-acetoxybenzoylglycylglycine.
- Subjects
CEREBRAL ischemia; POTASSIUM salts; CHEMICAL reactions; CHEMICAL synthesis; HETEROCYCLIC compounds
- Publication
Pharmaceutical Chemistry Journal, 2018, Vol 52, Issue 1, p37
- ISSN
0091-150X
- Publication type
Article
- DOI
10.1007/s11094-018-1762-0