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- Title
MetNetMaker: a free and open-source tool for the creation of novel metabolic networks in SBML format.
- Authors
Forth, Thomas; McConkey, Glenn A.; Westhead, David R.
- Abstract
Summary: An application has been developed to help with the creation and editing of Systems Biology Markup Language (SBML) format metabolic networks up to the organism scale. Networks are defined as a collection of Kyoto Encyclopedia of Genes and Genomes (KEGG) LIGAND reactions with an optional associated Enzyme Classification (EC) number for each reaction. Additional custom reactions can be defined by the user. Reactions within the network can be assigned flux constraints and compartmentalization is supported for each reaction in addition to the support for reactions that occur across compartment boundaries. Exported networks are fully SBML L2V4 compatible with an optional L2V1 export for compatibility with old versions of the COBRA toolbox.
- Subjects
SYSTEMS biology; COMPUTATIONAL biology; MOLECULAR biology; BIOINFORMATICS; DATABASES
- Publication
Bioinformatics, 2010, Vol 26, Issue 18, p2352
- ISSN
1367-4803
- Publication type
Article
- DOI
10.1093/bioinformatics/btq425