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- Title
Regorafenib Also Can Cause Osteonecrosis of the Jaw.
- Authors
Antonuzzo, Lorenzo; Lunghi, Alice; Giommoni, Elisa; Brugia, Marco; Di Costanzo, Francesco
- Abstract
The article offers information about osteonecrosis of the jaws (ONJ), a complication emerging in patients treated with bisphosphonates for bone metastases. It discusses the link between ONJ and denosumab, an antireceptor activator of nuclear factor kappa-B ligand monoclonal antibody, as well as regorafenib, a small-molecule multikinase inhibitor.
- Subjects
OSTEONECROSIS; JAW diseases; REGORAFENIB; IMMUNOGLOBULINS; ANTIGENS; ANTINEOPLASTIC agents; COLON tumors; COMPUTED tomography; PYRIDINE; RECTUM tumors; UREA
- Publication
JNCI: Journal of the National Cancer Institute, 2016, Vol 108, Issue 4, p1
- ISSN
0027-8874
- Publication type
case study
- DOI
10.1093/jnci/djw002