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- Title
Neuropsychiatric Symptoms in Korean Patients with Alzheimer’s Disease: Exploratory Factor Analysis and Confirmatory Factor Analysis of the Neuropsychiatric Inventory.
- Authors
Kang, Hyo Shin; Ahn, Inn Sook; Kim, Ji Hae; Kim, Doh Kwan
- Abstract
Background/Aims: We designed this study to examine subsyndromes in Korean patients with Alzheimer’s disease (AD) using exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Methods: Initial participants were 778 AD patients recruited from the Clinical Research Center for Dementia of South Korea and assessed via the Korean Neuropsychiatric Inventory. Those with ≥1 neuropsychiatric symptom were randomly divided into groups. Principal axis factoring with oblimin rotation was used to analyze group 1 inventory results, and maximum likelihood estimation extraction with Bollen-Stine bootstrapping was used for group 2. Results: The results of the EFA showed the presence of 4 subsyndromes: hyperactivity, affect, psychosis and apathy/vegetative symptom. The CFA results indicated this model was the best-fitting model for explaining these subsyndromes. Conclusion: Our model showed the best fit and identified 4 subsyndromes. This study might contribute to a clearer understanding of the neuropsychiatric symptoms in AD. Copyright © 2010 S. Karger AG, Basel
- Subjects
SOUTH Korea; ALZHEIMER'S disease; FACTOR analysis; DEMENTIA; SYNDROMES
- Publication
Dementia & Geriatric Cognitive Disorders, 2010, Vol 29, Issue 1, p82
- ISSN
1420-8008
- Publication type
Article
- DOI
10.1159/000264629