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- Title
EFFECTS OF PULMONARY HYPERTENSION ON EARLY OUTCOMES AFTER MITRAL VALVE REPLACEMENT.
- Authors
Paras, Iftikhar; Azam, Hammad; Khaki, Allah Buksh; Baig, Mirza Ahmad Raza; Rao, Shaukat Ali
- Abstract
Objectives: The objective of this study was to determine the safety of Mitral valve replacement surgery in the presence of severe pulmonary hypertension. Methodology: This was a randomized control trial in Chudhary Pervaiz Elahi Institute of Cardiology. Patients of Mitral stenosis undergoing Elective Mitral valve Replacement were included in this study. In Group I, there were patients with moderate pulmonary hypertension (30-60 mm of Hg) and in Group II patients with severe pulmonary hypertension (>60 mm of Hg) were included. Results: Patients included in the study were 30, with 15 in each group. There was no significant difference in age, gender, and other risk factors i.e. smoking, diabetes, and obesity in both groups. However pre-operative CVP was significantly high in Group II patients (p = 0.05). CPB times, need of inotropes and nitrates, and number of patients with prolonged ventilation time were significantly high in Group II (p >0.0001, 0.02, 0.003 and 0.02 respectively). There was significant decrease in Pulmonary Artery Pressures after surgery in Group I and II (p >0.0001, >0.0001 respectively). Regression analysis showed strong correlation between pulmonary artery pressures before surgery and after surgery (ß=0.708). Conclusions: Mitral valve replacement should be offered even in the presence of severe pulmonary hypertension, however these patients need extra postoperative care due to increased morbidity.
- Subjects
PULMONARY hypertension; MITRAL stenosis; HYPERTENSION risk factors
- Publication
Pakistan Heart Journal, 2015, Vol 48, Issue 2, p96
- ISSN
0048-2706
- Publication type
Article