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- Title
Comparison of Virtual Touch Tissue Quantification and Virtual Touch Tissue Imaging Quantification for diagnosis of solid breast tumors of different sizes.
- Authors
Ying-pei Chen; Ting Han; Rong Wu; Ming-hua Yao; Guang Xu; Li-xia Zhao; Hui Liu; Huan Pu; Yan Fang
- Abstract
BACKGROUND: Acoustic radiation force impulse imaging (ARFI) with Virtual Touch Tissue Quantification (VTQ) or Virtual Touch Tissue Imaging Quantification (VTIQ) measures shear wave velocity (SWV), which is proportional to tissue stiffness, a diagnostic parameter for malignancy. OBJECTIVE: To compare the performance of VTQ and VTIQ in diagnosing solid breast tumors. METHODS: Conventional ultrasound, VTQ and VTIQ were used to examine 246 solid breast tumors from 230 patients. Tumors were grouped according to size: <10 mm, 10-20 mm, >20 mm. Pathological diagnoses were via histological examination of biopsies. ROC curves were used to assess diagnostic performance and optimal cut-off points for VTQ and VTIQ. RESULTS: For all sizes, SWVVTQ and SWVVTIQ were higher for malignant versus benign tumors (P < 0.05). SWVVTQ and SWVVTIQ were both higher for tumors=10mm (P < 0.05). Areas under the ROC curves (diagnostic performance index; 0.860-0.952) did not differ significantly between VTQ and VTIQ. Optimal cut-off values for SWVVTQ and SWVVTIQ were higher for tumors=10 mm. CONCLUSION: The diagnostic performance of VTQ and VTIQ was moderate to good for solid breast tumors. Although both methods have higher sensitivities in tumors=10 mm, their overall diagnostic performance was similar for all sizes.
- Subjects
VIRTUAL reality in medicine; BREAST tumor diagnosis; SHEAR waves; BIOPSY; COMPARATIVE studies
- Publication
Clinical Hemorheology & Microcirculation, 2016, Vol 64, Issue 2, p235
- ISSN
1386-0291
- Publication type
Article
- DOI
10.3233/CH-16192