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- Title
A Novel Method of Obtaining Platelet Rich Fibrin from Rats and Quantifying Platelet Count.
- Authors
GRECU, ALEXANDRU FLORIAN; GRECU, DAN CRISTIAN; NICA, OLIVIU; CIUCA, EDUARD MIHAI; CAMEN, ADRIAN; CIUREA, MARIUS EUGEN
- Abstract
Background and objectives: Rat experimentation is the first line of research by which a medical hypothesis is usually tested. Platelet Rich Fibrin (PRF) is a relatively new bio-material that has shown promise to enhance healing in the field of bone research and tissue engineering. In order to perform PRF based experiments on rats, a proper protocol of obtaining PRF from rats needs to be established. Materials and Methods: 35 Wistar rats were used to obtain PRF by using cardiac puncture blood draw and quick subsequent centrifugation. The PRF samples were analyzed and compared to standard literature PRF composition. Results: PRF samples analysis showed persistent results pertaining to known PRF composition. Conclusions: Our experiment has shown that our protocol of obtaining PRF is capable of providing high quality PRF from rats.
- Subjects
PLATELET count; FIBRIN; RATS; PLATELET-rich fibrin
- Publication
Current Health Sciences Journal, 2019, Vol 45, Issue 1, p104
- ISSN
2067-0656
- Publication type
Article
- DOI
10.12865/CHSJ.45.01.14