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Experimental Validation of Bioinformatically Prioritized Therapeutic Hypotheses and Targets for Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.078862
By:
- Cary, Gregory A.;
- Wiley, Jesse C;
- Li, Qianjin;
- Nwakamma, Richard;
- Du, Yuhong;
- Zoeller, Elizabeth;
- Duong, Duc M.;
- Fu, Haian;
- Seyfried, Nicholas T;
- Levey, Allan I.;
- Betarbet, Ranjita;
- Carter, Gregory W;
- Center, The Emory‐Sage‐SGC TREAT‐AD
Publication type:
Article
Efforts toward discovering inhibitors of the SYK SH2–FCER1γ interaction as potential Alzheimer's disease chemical probes and therapeutics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076479
By:
- Sikdar, Arunima;
- Bashore, Frances M.;
- Katis, Vittorio;
- Bradshaw, William;
- Rygiel, Karolina;
- Du, Yuhong;
- Wang, Dongxue;
- Leisner, Tina;
- Hardy, Brian P.;
- Kireev, Dmitri B.;
- Pearce, Kenneth H.;
- Fu, Haian;
- Frye, Stephen V.;
- Axtman, Alison D.
Publication type:
Article
Towards the development of a chemical probe targeting the disruption of SYK tandem SH2 domain and FCεR1γ interactions for Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.067392
By:
- Potjewyd, Frances M.;
- Katis, Vittorio;
- Du, Yuhong;
- Bradshaw, William;
- Sikdar, Arunima;
- Nwogbo, Felix;
- Leisner, Tina;
- Wang, Dongxue;
- Hardy, Brian P.;
- Kireev, Dmitri B.;
- Pearce, Kenneth H.;
- Fu, Haian;
- Frye, Stephen V.;
- Axtman, Alison D.
Publication type:
Article
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Published in:
PLoS ONE, 2024, v. 19, n. 2, p. 1, doi. 10.1371/journal.pone.0293548
By:
- Bashore, Frances M.;
- Katis, Vittorio L.;
- Du, Yuhong;
- Sikdar, Arunima;
- Wang, Dongxue;
- Bradshaw, William J.;
- Rygiel, Karolina A.;
- Leisner, Tina M.;
- Chalk, Rod;
- Mishra, Swati;
- Williams, C. Andrew;
- Gileadi, Opher;
- Brennan, Paul E.;
- Wiley, Jesse C.;
- Gockley, Jake;
- Cary, Gregory A.;
- Carter, Gregory W.;
- Young, Jessica E.;
- Pearce, Kenneth H.;
- Fu, Haian
Publication type:
Article
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
Published in:
Pharmaceutical Research, 2023, v. 40, n. 9, p. 2133, doi. 10.1007/s11095-023-03596-9
By:
- Kelvin, James M.;
- Jain, Juhi;
- Thapa, Aashis;
- Qui, Min;
- Birnbaum, Lacey A.;
- Moore, Samuel G.;
- Zecca, Henry;
- Summers, Ryan J.;
- Switchenko, Jeffrey M.;
- Costanza, Emma;
- Uricoli, Biaggio;
- Wang, Xiaodong;
- Jui, Nathan T.;
- Fu, Haian;
- Du, Yuhong;
- DeRyckere, Deborah;
- Graham, Douglas K.;
- Dreaden, Erik C.
Publication type:
Article
Halogen bonds and other noncovalent interactions in the crystal structures of trans-1,2-diiodo alkenes: an ab initio and QTAIM study.
Published in:
Journal of Molecular Modeling, 2020, v. 26, n. 11, p. 1, doi. 10.1007/s00894-020-04591-2
By:
- Yuan, Yongna;
- Mills, Matthew J. L.;
- Li, Fuyang;
- Du, Yuhong;
- Wei, Jiaxuan;
- Su, Wei
Publication type:
Article
Melphalan induces cardiotoxicity through oxidative stress in cardiomyocytes derived from human induced pluripotent stem cells.
Published in:
Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-01984-1
By:
- Liu, Rui;
- Li, Dong;
- Sun, Fangxu;
- Rampoldi, Antonio;
- Maxwell, Joshua T.;
- Wu, Ronghu;
- Fischbach, Peter;
- Castellino, Sharon M.;
- Du, Yuhong;
- Fu, Haian;
- Mandawat, Anant;
- Xu, Chunhui
Publication type:
Article
Nonlinear Effects of Human Capital on TFP: Evidence from Eight ASEAN Countries.
Published in:
Journal of Economic Cooperation & Development, 2017, v. 38, n. 4, p. 1
By:
- Du Yuhong;
- Md Nor, Abu Hassan Shaari;
- Sarmidi, Tamat
Publication type:
Article
A multiplexed time-resolved fluorescence resonance energy transfer ultrahigh-throughput screening assay for targeting the SMAD4–SMAD3–DNA complex.
Published in:
Journal of Molecular Cell Biology, 2023, v. 15, n. 11, p. 1, doi. 10.1093/jmcb/mjad068
By:
- Ouyang, Wukun;
- Li, Qianjin;
- Niu, Qiankun;
- Qui, Min;
- Fu, Haian;
- Du, Yuhong;
- Mo, Xiulei
Publication type:
Article
TMPRSS2 and SARS-CoV-2 SPIKE interaction assay for uHTS.
Published in:
Journal of Molecular Cell Biology, 2023, v. 15, n. 3, p. 1, doi. 10.1093/jmcb/mjad017
By:
- Cicka, Danielle;
- Niu, Qiankun;
- Qui, Min;
- Qian, Kun;
- Miller, Eric;
- Fan, Dacheng;
- Mo, Xiulei;
- Ivanov, Andrey A;
- Sarafianos, Stefan G;
- Du, Yuhong;
- Fu, Haian
Publication type:
Article
Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening.
Published in:
Journal of Molecular Cell Biology, 2020, v. 12, n. 8, p. 630, doi. 10.1093/jmcb/mjaa036
By:
- Du, Yuhong;
- Li, Xingnan;
- Niu, Qiankun;
- Mo, Xiulei;
- Qui, Min;
- Ma, Tingxuan;
- Kuo, Calvin J;
- Fu, Haian
Publication type:
Article
NSD3S stabilizes MYC through hindering its interaction with FBXW7.
Published in:
Journal of Molecular Cell Biology, 2020, v. 12, n. 6, p. 438, doi. 10.1093/jmcb/mjz098
By:
- Gonzalez-Pecchi, Valentina;
- Kwan, Albert K;
- Doyle, Sean;
- Ivanov, Andrey A;
- Du, Yuhong;
- Fu, Haian
Publication type:
Article
Enabling systematic interrogation of protein--protein interactions in live cells with a versatile ultra-high-throughput biosensor platform.
Published in:
Journal of Molecular Cell Biology, 2016, v. 8, n. 3, p. 271, doi. 10.1093/jmcb/mjv064
By:
- Xiu-Lei Mo;
- Yin Luo;
- Ivanov, Andrei A.;
- Rina Su;
- Havel, Jonathan J.;
- Zenggang Li;
- Khuri, Fadlo R.;
- Yuhong Du;
- Haian Fu
Publication type:
Article
Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus.
Published in:
Biomolecules (2218-273X), 2023, v. 13, n. 6, p. 937, doi. 10.3390/biom13060937
By:
- Prikryl, David;
- Marin, Mariana;
- Desai, Tanay M.;
- Du, Yuhong;
- Fu, Haian;
- Melikyan, Gregory B.
Publication type:
Article
Longitudinal tear detection method for conveyor belt based on multi-mode fusion.
Published in:
Wireless Networks (10220038), 2024, v. 30, n. 4, p. 2839, doi. 10.1007/s11276-024-03693-6
By:
- Wang, Yimin;
- Du, Yuhong;
- Miao, Changyun;
- Miao, Di;
- Zheng, Yao;
- Yang, Dengjie
Publication type:
Article
Photic Regulation of Arylalkylamine N-Acetyltransferase Binding to 14-3-3 Proteins in Retinal Photoreceptor Cells.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 36, p. 9153, doi. 10.1523/JNEUROSCI.1384-06.2006
By:
- Pozdeyev, Nikita;
- Taylor, Carla;
- Haque, Rashidul;
- Chaurasia, Shyam S.;
- Visser, Amy;
- Thazyeen, Aamera;
- Yuhong Du;
- Haian Fu;
- Weller, Joan;
- Klein, David C.;
- Iuvone, P. Michael
Publication type:
Article
Coordinated development of the economy, society and environment in urban China: a case study of 285 cities.
Published in:
Environment, Development & Sustainability, 2022, v. 24, n. 11, p. 12917, doi. 10.1007/s10668-021-01975-z
By:
- Wang, Jiankang;
- Han, Qian;
- Du, Yuhong
Publication type:
Article
Wage Bargaining Power of Internal Migrant Workers: Evidence from Urban Labor Market in China.
Published in:
SAGE Open, 2024, v. 14, n. 2, p. 1, doi. 10.1177/21582440241259934
By:
- Yuhong Du;
- Shahiri, Hazrul
Publication type:
Article
Mechanisms of SPOP mutant‐mediated oncogenesis.
Published in:
FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04551
By:
- Doyle, Sean;
- Gu, Ling;
- Mo, Xiulei;
- Ivanov, Andrey;
- Niu, Qiankun;
- Du, Yuhong;
- Fu, Haian
Publication type:
Article
Tumor microenvironment in a minipig model of spinal cord glioma.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04531-7
By:
- Tora, Muhibullah S.;
- Neill, Stewart G.;
- Lakhina, Yuliya;
- Assed, Hemza;
- Zhang, Michelle;
- Nagarajan, Purva P.;
- Federici, Thais;
- Gutierrez, Juanmarco;
- Hoang, Kimberly B.;
- Du, Yuhong;
- Lei, Kecheng;
- Boulis, Nicholas M.
Publication type:
Article
The Impact of Higher Education and Human Capital Quality on "Local-Neighborhood" Economic Growth.
Published in:
Best Evidence in Chinese Education, 2021, v. 8, n. 1, p. 1041, doi. 10.15354/bece.21.ar22
By:
- Ran Zhao;
- Yuhong Du
Publication type:
Article
Optimization of Smart Textiles Robotic Arm Path Planning: A Model-Free Deep Reinforcement Learning Approach with Inverse Kinematics.
Published in:
Processes, 2024, v. 12, n. 1, p. 156, doi. 10.3390/pr12010156
By:
- Zhao, Di;
- Ding, Zhenyu;
- Li, Wenjie;
- Zhao, Sen;
- Du, Yuhong
Publication type:
Article
Cascaded Fuzzy Reward Mechanisms in Deep Reinforcement Learning for Comprehensive Path Planning in Textile Robotic Systems.
Published in:
Applied Sciences (2076-3417), 2024, v. 14, n. 2, p. 851, doi. 10.3390/app14020851
By:
- Zhao, Di;
- Ding, Zhenyu;
- Li, Wenjie;
- Zhao, Sen;
- Du, Yuhong
Publication type:
Article
Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease.
Published in:
Nature Communications, 2017, v. 8, n. 3, p. 14740, doi. 10.1038/ncomms14740
By:
- Zhang, Zhentao;
- Obianyo, Obiamaka;
- Dall, Elfriede;
- Du, Yuhong;
- Fu, Haian;
- Liu, Xia;
- Kang, Seong Su;
- Song, Mingke;
- Yu, Shan-Ping;
- Cabrele, Chiara;
- Schubert, Mario;
- Li, Xiaoguang;
- Wang, Jian-Zhi;
- Brandstetter, Hans;
- Ye, Keqiang
Publication type:
Article
cAMP/adenylyl cyclase stimulation promotes 14-3-3 binding to UT-A1 urea transporter.
Published in:
FASEB Journal, 2007, v. 21, n. 6, p. A906
By:
- Guangping Chen;
- Zenggang Li;
- Klein, Janet D.;
- Yuan Yang;
- Fröhlich, Otto;
- Yuhong Du;
- Haian Fu;
- Sands, Jeff M.
Publication type:
Article
High expression of MKK3 is associated with worse clinical outcomes in African American breast cancer patients.
Published in:
2020
By:
- Yang, Xuan;
- Amgad, Mohamed;
- Cooper, Lee A. D.;
- Du, Yuhong;
- Fu, Haian;
- Ivanov, Andrey A.
Publication type:
journal article
Development of a Time-Resolved Fluorescence Resonance Energy Transfer Ultrahigh-Throughput Screening Assay for Targeting the NSD3 and MYC Interaction.
Published in:
Assay & Drug Development Technologies, 2018, v. 16, n. 2, p. 96, doi. 10.1089/adt.2017.835
By:
- Jinglin Xiong;
- Pecchi, Valentina Gonzalez;
- Min Qui;
- Ivanov, Andrey A.;
- Xiulei Mo;
- Qiankun Niu;
- Xiang Chen;
- Haian Fu;
- Yuhong Du
Publication type:
Article
Screening and Functional Profiling of Small-Molecule HIV-1 Entry and Fusion Inhibitors.
Published in:
Assay & Drug Development Technologies, 2017, v. 15, n. 2, p. 53, doi. 10.1089/adt.2017.777
By:
- Giroud, Charline;
- Du, Yuhong;
- Marin, Mariana;
- Min, Qui;
- Jui, Nathan T.;
- Fu, Haian;
- Melikyan, Gregory B.
Publication type:
Article
High-Throughput HIV-Cell Fusion Assay for Discovery of Virus Entry Inhibitors.
Published in:
Assay & Drug Development Technologies, 2015, v. 13, n. 3, p. 155, doi. 10.1089/adt.2015.639
By:
- Marin, Mariana;
- Du, Yuhong;
- Giroud, Charline;
- Kim, Jeong Hwa;
- Qui, Min;
- Fu, Haian;
- Melikyan, Gregory B.
Publication type:
Article
A Time-Resolved Fluorescence Resonance Energy Transfer Assay for High-Throughput Screening of 14-3-3 Protein-Protein Interaction Inhibitors.
Published in:
Assay & Drug Development Technologies, 2013, v. 11, n. 6, p. 367, doi. 10.1089/adt.2013.507
By:
- Du, Yuhong;
- Fu, Robert W.;
- Lou, Bin;
- Zhao, Jing;
- Qui, Min;
- Khuri, Fadlo R.;
- Fu, Haian
Publication type:
Article
A Dual-Readout F2Assay That Combines Fluorescence Resonance Energy Transfer and Fluorescence Polarization for Monitoring Bimolecular Interactions.
Published in:
Assay & Drug Development Technologies, 2011, v. 9, n. 4, p. 382, doi. 10.1089/adt.2010.0292
By:
- Yuhong Du;
- Zaneta Nikolovska-Coleska;
- Min Qui;
- Lian Li;
- Iestyn Lewis;
- Raymond Dingledine;
- Jeanne A. Stuckey;
- Krzysztof Krajewski;
- Peter P. Roller;
- Shaomeng Wang;
- Haian Fu
Publication type:
Article
Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κ B pathway.
Published in:
International Journal of Cancer, 2015, v. 136, n. 10, p. 2341, doi. 10.1002/ijc.29301
By:
- Ramachandiran, Sampath;
- Adon, Arsene;
- Guo, Xiangxue;
- Wang, Yi;
- Wang, Huichen;
- Chen, Zhengjia;
- Kowalski, Jeanne;
- Sunay, Ustun R.;
- Young, Andrew N.;
- Brown, Theresa;
- Mar, Jessica C.;
- Du, Yuhong;
- Fu, Haian;
- Mann, Karen P.;
- Natkunam, Yasodha;
- Boise, Lawrence H.;
- Saavedra, Harold I.;
- Lossos, Izidore S.;
- Bernal‐Mizrachi, Leon
Publication type:
Article
MEDICI: Mining Essentiality Data to Identify Critical Interactions for Cancer Drug Target Discovery and Development.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170339
By:
- Harati, Sahar;
- Cooper, Lee A. D.;
- Moran, Josue D.;
- Giuste, Felipe O.;
- Du, Yuhong;
- Ivanov, Andrei A.;
- Johns, Margaret A.;
- Khuri, Fadlo R.;
- Fu, Haian;
- Moreno, Carlos S.
Publication type:
Article
Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models.
Published in:
British Journal of Cancer, 2023, v. 129, n. 5, p. 884, doi. 10.1038/s41416-023-02359-y
By:
- Li, Xin;
- Chen, Yanhua;
- Bai, Lijuan;
- Zhao, Rui;
- Wu, Yifei;
- Xie, Zhong-Ru;
- Wu, Jason M.;
- Bowen, Nathan J.;
- Danaher, Alira;
- Cook, Nicholas;
- Li, Dehong;
- Qui, Min;
- Du, Yuhong;
- Fu, Haian;
- Osunkoya, Adeboye O.;
- Kucuk, Omer;
- Wu, Daqing
Publication type:
Article
Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer.
Published in:
Theranostics, 2021, v. 11, n. 14, p. 6873, doi. 10.7150/thno.49235
By:
- Xin Li;
- Gera, Lajos;
- Shumin Zhang;
- Yanhua Chen;
- Lei Lou;
- Wilson, Lauren Marie;
- Zhong-Ru Xie;
- Sautto, Giuseppe;
- Degang Liu;
- Danaher, Alira;
- Mamouni, Kenza;
- Yang Yang;
- Yuhong Du;
- Haian Fu;
- Kucuk, Omer;
- Osunkoya, Adeboye O.;
- Jia Zhou;
- Daqing Wu
Publication type:
Article
Discovery of a dual inhibitor of NQO1 and GSTP1 for treating glioblastoma.
Published in:
Journal of Hematology & Oncology, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13045-020-00979-y
By:
- Lei, Kecheng;
- Gu, Xiaoxia;
- Alvarado, Alvaro G.;
- Du, Yuhong;
- Luo, Shilin;
- Ahn, Eun Hee;
- Kang, Seong Su;
- Ji, Bing;
- Liu, Xia;
- Mao, Hui;
- Fu, Haian;
- Kornblum, Harley I.;
- Jin, Lingjing;
- Li, Hua;
- Ye, Keqiang
Publication type:
Article
Discovering Small-Molecule Estrogen Receptor α/Coactivator Binding Inhibitors: High-Throughput Screening, Ligand Development, and Models for Enhanced Potency.
Published in:
ChemMedChem, 2011, v. 6, n. 4, p. 654, doi. 10.1002/cmdc.201000507
By:
- Sun, Aiming;
- Moore, Terry W.;
- Gunther, Jillian R.;
- Kim, Mi-Sun;
- Rhoden, Eric;
- Du, Yuhong;
- Fu, Haian;
- Snyder, James P.;
- Katzenellenbogen, John A.
Publication type:
Article
The OncoPPi Portal: an integrative resource to explore and prioritize protein-protein interactions for cancer target discovery.
Published in:
Bioinformatics, 2018, v. 34, n. 7, p. 1183, doi. 10.1093/bioinformatics/btx743
By:
- Ivanov, Andrei A;
- Revennaugh, Brian;
- Rusnak, Lauren;
- Gonzalez-Pecchi, Valentina;
- Mo, Xiulei;
- Johns, Margaret A;
- Du, Yuhong;
- Cooper, Lee A D;
- Moreno, Carlos S;
- Khuri, Fadlo R
Publication type:
Article
Composition, characteristics, and treatment technologies of condensable particulate matter present in flue gas emitted by coking plants in China.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-59098-0
By:
- Wang, Chunyan;
- Du, Yuhong;
- Yan, Bo;
- Dong, Yonggang;
- Zhao, Zhihui;
- Shen, Jinchao;
- Guo, Mengxia;
- Zhang, Zhaochi
Publication type:
Article
Research on the construction of weaponry indicator system and intelligent evaluation methods.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-46660-5
By:
- Wang, Shuai;
- Du, Yuhong;
- Zhao, Shuaijie;
- Hao, Jinhu;
- Gan, Lian
Publication type:
Article
Human beige adipocytes for drug discovery and cell therapy in metabolic diseases.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16340-3
By:
- Singh, Amar M.;
- Zhang, Liang;
- Avery, John;
- Yin, Amelia;
- Du, Yuhong;
- Wang, Hui;
- Li, Zibo;
- Fu, Haian;
- Yin, Hang;
- Dalton, Stephen
Publication type:
Article
Prospective evaluation and success of a machine learning hit-to-lead drug development program against phosphatidylinositol 3-kinase α.
Published in:
ARKIVOC: Online Journal of Organic Chemistry, 2021, v. 2021, p. 25, doi. 10.24820/ark.5550190.p011.304
By:
- Kaiser, Thomas M.;
- Dentmon, Zackery W.;
- Burger, Pieter B.;
- Qi Shi;
- Snyder, James P.;
- Yuhong Du;
- Haian Fu;
- Liotta, Dennis C.
Publication type:
Article

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