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- Title
Albumin, haemoglobin, BMI and cognitive performance in older adults.
- Authors
Te-Pin Ng; Lei Feng; Niti, Mathew; Keng Bee Yap
- Abstract
Objectives: to examine the relationships between serum albumin, haemoglobin and body mass index (BMI) with cognitive performance among community-living older adults. Method: design-population-based cross-sectional study; setting-local community in Southeast Region of Singapore; subjects-Chinese older adults aged 55 and above (N = 2,550); measurements-serum albumin, haemoglobin, BMI and Mini-Mental State Examination (MMSE). Results: in multivariable analyses controlling for gender, age, education and vascular risk factors, low albumin in the bottom quintile (OR 2.04; 95% CI 1.22-3.41) and low haemoglobin in the bottom quintile (OR 1.56; 95% CI 1.00-2.47) and low BMI with chronic comorbidity (OR 1.73; 95%CT 1.02-2.95) were independently associated with poor cognitive performance (MMSE ≥ 23). Among cognitively intact respondents (MMSE ≤ 24), albumin concentration showed a significant inverse linear relationship with MMSE scores (P for trend =0.002). Conclusion: low albumin, low haemoglobin and low BMI (in the presence of chronic comorbidity) are independently associated with poor cognitive performance in community-living older adults.
- Subjects
ALBUMINS; OLDER people; BODY mass index; POPULATION; RESEARCH
- Publication
Age & Ageing, 2008, Vol 37, Issue 4, p423
- ISSN
0002-0729
- Publication type
Article
- DOI
10.1093/ageing/afn102