We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids.
- Authors
Morgan, Dáiríne M.; Lam, Hon Wai; Guiry, Patrick J.
- Abstract
Herein we report a syn‐arylnickelative cyclisation with ketone‐ and imine‐tethered terminal alkynes (16 examples) in yields of up to 89 %. The reaction proceeds via a syn‐aryl nickelation of a terminal alkyne followed by cyclisation of the resulting alkenylnickel species onto the ketone or imine. The enantioselective version of this transformation has also been explored with enantioselectivities of up to 83 : 17 er observed.
- Subjects
RING formation (Chemistry); ALKYNES; KETONES; ACIDS
- Publication
European Journal of Organic Chemistry, 2024, Vol 27, Issue 23, p1
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.202400445