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- Title
Therapy of relapsing minimal-change disease in adults: a new approach?
- Authors
Glassock, Richard J
- Abstract
Multiple-relapsing minimal-change disease (MCD) often requires exposure to potentially toxic agents in an attempt to achieve a lasting remission of nephrotic syndrome. Munyentwali and co-workers describe an experience using rituximab in adults with multiple-relapsing MCD that supports both efficacy and safety of this agent. However, the optimal dosing regimen and mechanism of action remain unclear. Thus, randomized controlled trials are warranted in both adults and children to better define the role of rituximab in multiple-relapsing MCD.
- Subjects
DISEASES in adults; POISONS; NEPHROTIC syndrome; DISEASE remission; RITUXIMAB
- Publication
Kidney International, 2013, Vol 83, Issue 3, p343
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.2012.412