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- Title
Anaemia is common and predicts mortality in diabetic nephropathy.
- Authors
N. Joss; R. Patel; K. Paterson; K. Simpson; C. Perry; C. Stirling
- Abstract
Background: Diabetes is the single largest cause of chronic renal failure, accounting for 18% of patients on renal replacement therapy in the UK. Aim: To investigate the chronic kidney disease stage at which patients with diabetic nephropathy are referred to renal services, determine the prevalence of anaemia in patients with diabetic nephropathy, examine patient outcome and identity prognostic factors. Design: Retrospective review. Methods: Patients with diabetic nephropathy referred to our renal services between 1989 and 2004 were identified from electronic records. Estimated glomerular filtration rate (calculated using the MDRD formula) and haemoglobin at referral were collected. Times to renal replacement therapy and death were noted. Results: We identified 508 patients. At referral, mean eGFR was 34 ml/min/1.73 m2 and 48% of patients were at CKD stages 4 and 5. Mean haemoglobin was 11.7 g/dl; 21% had a haemoglobin Discussion: At referral to renal services, almost 50% of patients with diabetic nephropathy were at CKD stages 4 and 5. Anaemia was common and predicted mortality. All diabetic patients from CKD stage 3 should be screened for anaemia. We believe that patients with diabetic nephropathy should be discussed with renal services when they reach CKD stage 3 with evidence of progression of renal disease.
- Subjects
DIABETES; DIABETES complications; ANEMIA; CHRONIC kidney failure
- Publication
QJM: An International Journal of Medicine, 2007, Vol 100, Issue 10, p641
- ISSN
1460-2725
- Publication type
Article
- DOI
10.1093/qjmed/hcm080