Comments on M. Satoh and his colleagues' findings concerning the increased levels of malondialdehyde, advanced glycation end products (AGE) and 8-hydroxyl 2-deoxyguanosine (8-OHdG) markers of lipid, protein and DNA oxidation when patients where dialyzed with a high permeability membrane. Failure to describe estimate of the molecular size of the species of AGE and 8-OHdG; Inappropriateness of the statistic used.