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- Title
Primary Melanoma Tumors from CDKN2A Mutation Carriers Do Not Belong to a Distinct Molecular Subclass.
- Authors
Staaf, Johan; Harbst, Katja; Lauss, Martin; Ringnér, Markus; Måsbäck, Anna; Howlin, Jillian; Jirström, Karin; Harland, Mark; Zebary, Abdlsattar; Palmer, Jane M; Ingvar, Christian; Olsson, Håkan; Newton-Bishop, Julia; Hansson, Johan; Hayward, Nicholas; Gruis, Nelleke; Jönsson, Göran
- Abstract
The article presents a study which examines the exhibition of a distinct gene expression pattern by primary melanomas from CDKN2A mutation. Findings reveal that cutaneous malignant melanoma (CMM) from CDKN2A germline mutation carriers do not have a distinct gene expression subtype. Also given are the clinicopathological and molecular features of sporadic melanomas and melanomas from the CDKN2A.
- Subjects
GENE expression; MELANOMA; GENETIC mutation; GENETIC carriers; CLINICAL pathology; MOLECULAR genetics
- Publication
Journal of Investigative Dermatology, 2014, Vol 134, Issue 12, p3000
- ISSN
0022-202X
- Publication type
Article
- DOI
10.1038/jid.2014.272