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- Title
Salivary Flow Rate and Peritonsillar Abscess Development: A Prospective Cohort Study.
- Authors
Dang, Jennifer; Athavale, Sanjay M.; Teng, James; Fritz, Ryan; Phillips, Sharon; Campos, Elizabeth; Seibert, John
- Abstract
INTRODUCTION: While there are several theories for peritonsillar abscess (PTA) development, their exact pathogenesis is unknown. We propose that PTAs develop secondary to salivary stasis in the face of tonsillar inflammation. Patients who have a combination of dehydration and poor baseline salivary flow will be at a greater risk to subsequently develop ductal obstruction of Weber's glands (minor salivary glands of the superior tonsillar pillar), leading to further inflammation, cellulitis and PTA formation. METHODS: We compared the unstimulated and stimulated salivary flow rates in three groups of patients: (1) patients who have developed PTAs, (2) patients with chronic tonsillitis and no PTA history, (3) controls - patients who do not have chronic tonsillitis and have never developed a PTA. RESULTS: The average age for the PTA patients was 30, CT without PTA was 27, and controls was 24. The preliminary results showed that there is no significance between the three groups; further study with more patients is currently underway. CONCLUSIONS: Our study failed to find a different in salivary flow in our three groups of patients. We hope that when we reach our final patient count of 50/group the results may be different. If not, salivary flow may not play a role in the development of PTA.
- Subjects
LONGITUDINAL method; COHORT analysis; SALIVARY glands; CELLULITIS; TONSILLITIS
- Publication
Laryngoscope, 2011, Vol 121, Issue S5, pS244
- ISSN
0023-852X
- Publication type
Article
- DOI
10.1002/lary.22195