We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Biomimetic Diatom Biosilica and Its Potential for Biomedical Applications and Prospects: A Review.
- Authors
Min, Ki Ha; Kim, Dong Hyun; Youn, Sol; Pack, Seung Pil
- Abstract
Diatom biosilica is an important natural source of porous silica, with three-dimensional ordered and nanopatterned structures referred to as frustules. The unique features of diatom frustules, such as their high specific surface area, thermal stability, biocompatibility, and adaptable surface chemistry, render diatoms valuable materials for high value-added applications. These attributes make diatoms an exceptional cost-effective raw material for industrial use. The functionalization of diatom biosilica surface improves its biophysical properties and increases the potential applications. This review focuses on the potential uses of diatom biosilica including traditional approaches and recent progress in biomedical applications. Not only well-studied drug delivery systems but also promising uses on bone regeneration and wound healing are covered. Furthermore, considerable aspects and possible future directions for the use of diatom biosilica materials are proposed to develop biomedical applications and merit further exploration.
- Subjects
DIATOM frustules; DIATOMS; POROUS silica; DRUG delivery systems; BONE regeneration; SURFACE chemistry
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 4, p2023
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25042023