We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Tata Memorial Centre Evidence Based Management of Colorectal cancer.
- Authors
Saklani, Avanish; Kazi, Mufaddal; Desouza, Ashwin; Sharma, Ankit; Engineer, Reena; Krishnatry, Rahul; Gudi, Shivkumar; Ostwal, Vikas; Ramaswamy, Anant; Dhanwat, Aditya; Bhargava, Prabhat; Mehta, Shaesta; Sundaram, Sridhar; Kale, Aditya; Goel, Mahesh; Patkar, Shraddha; Vartey, Gurudutt; Kulkarni, Suyash; Baheti, Akshay; Ankathi, Suman
- Abstract
This review article examines the evidence-based management of colorectal cancers, focusing on topics characterized by ongoing debates and evolving evidence. To contribute to the scientific discourse, we intentionally exclude subjects with established guidelines, concentrating instead on areas where the current understanding is dynamic. Our analysis encompasses a thorough exploration of critical themes, including the evidence surrounding complete mesocolic excision and D3 lymphadenectomy in colon cancers. Additionally, we delve into the evolving landscape of perioperative chemotherapy in both colon and rectal cancers, considering its nuanced role in the context of contemporary treatment strategies. Advancements in surgical techniques are a pivotal aspect of our discussion, with an emphasis on the utilization of minimally invasive approaches such as laparoscopy and robotic surgery in both colon and rectal cancers, including advanced rectal cases. Moving beyond conventional radical procedures, we scrutinize the feasibility and implications of endoscopic resections for small tumors, explore the paradigm of organ preservation in locally advanced rectal cancers, and assess the utility of total neoadjuvant therapy in the current treatment landscape. Our final segment reviews pivotal trials that have significantly influenced the management of colorectal liver and peritoneal metastasis.
- Subjects
COLORECTAL cancer; COLORECTAL liver metastasis; COLON cancer; RECTAL cancer; ENDOSCOPIC surgery
- Publication
Indian Journal of Cancer, 2024, Vol 61, pS29
- ISSN
0019-509X
- Publication type
Article
- DOI
10.4103/ijc.ijc_66_24