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- Title
Study of Interaction between Human Hemoglobin and Antitubercular Isoniazid Drug with Its Detection.
- Authors
Patil, Shilpa R.; Mahanwar, Sunanda T.; Gunjal, Datta B.; Wakshe, Saubai B.; Anbhule, Prashant V.; Kolekar, Govind B.
- Abstract
The high intake of antitubercular isonicotinyl hydrazide (INH) is hazardous to human body. Hence, there is a need for its detection. For this reason, we study interaction between human hemoglobin (HHb) and INH by applying fluorescence and UV–vis spectroscopic techniques. Fluorimetric as well as UV–vis results showed the formation of complex between HHb and INH. The proposed HHb‐based fluorescence method was applied directly for the determination of INH in pharmaceutical sample.
- Subjects
ANTITUBERCULAR agents; SERUM albumin; SOCIAL interaction; HEMOGLOBINS; HUMAN body; FLUORESCENCE
- Publication
Macromolecular Symposia, 2019, Vol 387, Issue 1, pN.PAG
- ISSN
1022-1360
- Publication type
Article
- DOI
10.1002/masy.201800203