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- Title
Joint spatial-spectral reconstruction and k-t spirals for accelerated 2D spatial/1D spectral imaging of <sup>13</sup>C dynamics.
- Authors
Gordon, Jeremy W.; Niles, David J.; Fain, Sean B.; Johnson, Kevin M.
- Abstract
Purpose To develop a novel imaging technique to reduce the number of excitations and required scan time for hyperpolarized 13C imaging. Methods A least-squares based optimization and reconstruction is developed to simultaneously solve for both spatial and spectral encoding. By jointly solving both domains, spectral imaging can potentially be performed with a spatially oversampled single echo spiral acquisition. Digital simulations, phantom experiments, and initial in vivo hyperpolarized [1-13C]pyruvate experiments were performed to assess the performance of the algorithm as compared to a multi-echo approach. Results Simulations and phantom data indicate that accurate single echo imaging is possible when coupled with oversampling factors greater than six (corresponding to a worst case of pyruvate to metabolite ratio < 9%), even in situations of substantial
- Publication
Magnetic Resonance in Medicine, 2014, Vol 71, Issue 4, p1435
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.24796