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- Title
Efficacy and safety of home‐based 590 nm light‐emitting diodes and in‐hospital 1064 nm Q‐switched Nd:YAG laser in the treatment of facial melasma: A single‐centre, prospective, randomized clinical trial.
- Authors
Xuan, Y. J.; Dai, X. X.; Chen, L.; Xiang, L. H.; Jin, S. L.; Zhang, C. F.
- Abstract
A study was conducted to compare the efficacy and safety of home-based 590nm light-emitting diodes (LEDs) and in-hospital 1064nm Q-switched Nd:YAG laser in the treatment of facial melasma. Fifty patients were randomly assigned to either the LEDs group or the QSNY group and were followed up for 16 weeks. The results showed that both treatments significantly reduced the melasma area severity index (mMASI) scores, melanin index (MI), and erythema index (EI) in both groups. No statistical differences were found between the two groups, suggesting that home-based LEDs could be a promising alternative for melasma treatment due to its portability and low cost. The study was funded by the Medical Innovation Research Special Project of Shanghai Science and Technology Commission, the National Natural Science Foundation of China, and the Natural Science Foundation of Shanghai. No conflicts of interest were declared, and the data are available upon request.
- Subjects
ND-YAG lasers; Q-switched lasers; LIGHT emitting diodes; MELANOSIS; HAIR removal; CLINICAL trials; REJUVENATION; HYPERPIGMENTATION
- Publication
Journal of the European Academy of Dermatology & Venereology, 2024, Vol 38, Issue 2, pe162
- ISSN
0926-9959
- Publication type
Article
- DOI
10.1111/jdv.19510