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- Title
Variation over time of the factors influencing return to work and work capacities after a diagnosis of breast cancer: a study on the behalf of the Seintinelles research network.
- Authors
Hequet, Delphine; Hamy, Anne-Sophie; Girard, Noemie; Laas, Enora; Coussy, Florence; Rouzier, Roman; Preau, Marie; Delrieu, Lidia; Dumas, Agnes; Reyal, Fabien
- Abstract
<bold>Purpose: </bold>To evaluate the dynamics of the determinants of returning to work (RTW) in a population of patients treated for breast cancer (BC) in a real-world setting.<bold>Method: </bold>We conducted a retrospective study including 1278 BC patients working or looking for work at the time of diagnosis. We performed a focused principal component analysis to highlight the dimensions of a persistent decline in work capacity. Logistic regression analyses were performed to identify correlates of non-RTW 1 and 2 years after treatment.<bold>Results: </bold>One-third (31%, n = 389) of patients continued working during treatment. At study inclusion, 1100 patients had returned to work (89%). Three-quarters (n = 508, 75%) of the women reported a decline in work capacity 1 year after RTW and 22% (n = 148) presented a persistent decline in work capacity 2 years after the diagnosis. The odds ratio for non-RTW at 1 year was significantly higher for patients treated with a combination of chemotherapy and trastuzumab (OR = 1.72, 95% CI [1.07-2.76]), manual workers (OR = 3.99, 95% CI [1.54-10.81]), patients with lower incomes (OR = 2.33, 95% CI [1.29-4.19]), and patients experiencing fatigue (OR = 1.81, 95% CI [1.34-2.48]). The odds ratio for non-RTW at 2 years was higher for various occupational categories (OR = 3.49, 95% CI [1.89-6.74] for clerks, OR = 4.58, 95% CI [1.48-12.82] for self-employed workers, OR = 8.98, 95% CI [2.69-27.89] for manual workers), patients with comorbidities (OR = 2.80, 95% CI [1.61-4.93]), and patients experiencing anxiety symptoms (OR = 2.54, 95% CI [1.18-5.76]), while the impact of the type of treatment was no longer significantly associated with RTW.<bold>Conclusion: </bold>The determinants of RTW change over time. Patients should be offered supportive interventions tailored to risk factors and time from diagnosis.
- Subjects
BREAST tumor diagnosis; RETROSPECTIVE studies; EMPLOYMENT; EMPLOYMENT reentry; ANXIETY; BREAST tumors
- Publication
Supportive Care in Cancer, 2022, Vol 30, Issue 7, p5991
- ISSN
0941-4355
- Publication type
Article
- DOI
10.1007/s00520-022-07000-x