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- Title
Platelets Rich Plasma (PRP) Procedure in the Healing of Atonic Wounds.
- Authors
Horgos, Maur Sebastian; Pop, Ovidiu Laurean; Sandor, Mircea; Borza, Ioan Lucian; Negrean, Rodica Anamaria; Cote, Adrian; Neamtu, Andreea-Adriana; Grierosu, Carmen; Sachelarie, Liliana; Huniadi, Anca
- Abstract
(1) Background: Patients suffering from chronic wounds report physical, mental, and social consequences due to their existence and care. There is a global need for tissue repair strategies and, in our case, for chronic wound healing. PRP therapy is based on the fact that platelet-derived growth factors (PGF) support the three phases of the wound healing and repair cascade (inflammation, proliferation, and remodeling); (2) Methods: A comparative study was carried out on two groups of patients with atonic wounds totaling a total of 80 cases as follows: a study group in which the PRP procedure was applied and a control group in which the biological product was not injected. The study was carried out in the surgery clinic of the Clinical Hospital C.F. Oradea City; (3) Results: A much faster healing was achieved in the case of patients who benefited from the platelet-rich plasma injection therapy compared to the group of patients in whom this therapy was not used. Three weeks after the plasma injection, a considerable reduction of the wound was evident, with some of the patients presenting with a closed wound; (4) Conclusions: The effect of PRP on the healing of chronic wounds is promising in most cases. A positive effect was also highlighted in terms of reducing treatment costs by considerably reducing the materials used as well as the number of hospitalizations for the same pathology.
- Subjects
PLATELET-rich plasma; WOUND healing; PLATELET-derived growth factor; CHRONIC wounds &; injuries; SOCIAL impact
- Publication
Journal of Clinical Medicine, 2023, Vol 12, Issue 12, p3890
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm12123890