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- Title
Body Mass Index and Antibody Persistence after Measles, Mumps, Rubella and Hepatitis B Vaccinations.
- Authors
Fonzo, Marco; Nicolli, Annamaria; Maso, Stefano; Carrer, Lorenzo; Trevisan, Andrea; Bertoncello, Chiara
- Abstract
Overweight and obesity may cause a reduced response to vaccination. The purpose of the present research was to study the relationship between current body mass index (BMI) and antibody persistence after vaccination against measles, mumps, and rubella (MMR) and hepatitis B virus (HBV) given during childhood, as per the current vaccination schedule. The study was conducted on 2185 students at the School of Medicine, University of Padua, Italy. The mean age of the participants was 20.3 years. After adjusting for sex, age at first dose of vaccine administered, age at last dose, and age at study enrollment, no significant association was found between lack of serologic protection and BMI for either the HBV vaccine or each component of the MMR vaccine. For the first time, the absence of this relationship was demonstrated for the MMR vaccine. Given the evidence currently available, further research on BMI and vaccines in general remains desirable.
- Subjects
ITALY; HEPATITIS B vaccines; UNIVERSITA di Padova; BODY mass index; RUBELLA; MUMPS; MEASLES
- Publication
Vaccines, 2022, Vol 10, Issue 7, pN.PAG
- ISSN
2076-393X
- Publication type
Article
- DOI
10.3390/vaccines10071152