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- Title
Alkylation and acylation of C-phosphorylated acetamidines involving CH-acidic methylene group.
- Authors
Shishkin, V.; Mednikov, E.; Shevchenko, M.; Anishchenko, O.; Popov, Yu.
- Abstract
Reactions of sodium derivatives of C-phosphorylated acetamidines containing CH-acidic methylene group with alkyl and acyl halides were studied. The interaction occurs selectively to form the products of alkylation and acylation of methylene group, respectively. A convenient method for the synthesis of C-alkylated and C-acylated derivatives of C-phosphorylated acetamidines was developed.
- Subjects
SODIUM; ALKYLATION; ACYLATION; DICHLOROMETHANE; METHYL iodide; ETHYL bromide
- Publication
Russian Journal of General Chemistry, 2011, Vol 81, Issue 4, p642
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363211040049