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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.
Published in:
Cancer & Metabolism, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40170-019-0202-2
By:
- Nelson, Barbara S.;
- Lin, Lin;
- Kremer, Daniel M.;
- Sousa, Cristovão M.;
- Cotta-Ramusino, Cecilia;
- Myers, Amy;
- Ramos, Johanna;
- Gao, Tina;
- Kovalenko, Ilya;
- Wilder-Romans, Kari;
- Dresser, Joseph;
- Davis, Mary;
- Lee, Ho-Joon;
- Nwosu, Zeribe C.;
- Campit, Scott;
- Mashadova, Oksana;
- Nicolay, Brandon N.;
- Tolstyka, Zachary P.;
- Halbrook, Christopher J.;
- Chandrasekaran, Sriram
Publication type:
Article
GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24859-2
By:
- Kremer, Daniel M.;
- Nelson, Barbara S.;
- Lin, Lin;
- Yarosz, Emily L.;
- Halbrook, Christopher J.;
- Kerk, Samuel A.;
- Sajjakulnukit, Peter;
- Myers, Amy;
- Thurston, Galloway;
- Hou, Sean W.;
- Carpenter, Eileen S.;
- Andren, Anthony C.;
- Nwosu, Zeribe C.;
- Cusmano, Nicholas;
- Wisner, Stephanie;
- Mbah, Nneka E.;
- Shan, Mengrou;
- Das, Nupur K.;
- Magnuson, Brian;
- Little, Andrew C.
Publication type:
Article
Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.
Published in:
2018
By:
- Nwosu, Zeribe C.;
- Battello, Nadia;
- Rothley, Melanie;
- Piorońska, Weronika;
- Sitek, Barbara;
- Ebert, Matthias P.;
- Hofmann, Ute;
- Sleeman, Jonathan;
- Wölfl, Stefan;
- Meyer, Christoph;
- Megger, Dominik A.;
- Dooley, Steven
Publication type:
Correction Notice
Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, n. 1, p. N.PAG, doi. 10.1186/s13046-018-0872-6
By:
- Nwosu, Zeribe C.;
- Battello, Nadia;
- Rothley, Melanie;
- Piorońska, Weronika;
- Sitek, Barbara;
- Ebert, Matthias P.;
- Hofmann, Ute;
- Sleeman, Jonathan;
- Wölfl, Stefan;
- Meyer, Christoph;
- Megger, Dominik A.;
- Dooley, Steven
Publication type:
Article
Bone morphogenetic protein 9 as a key regulator of liver progenitor cells in DDC‐induced cholestatic liver injury.
Published in:
Liver International, 2018, v. 38, n. 9, p. 1664, doi. 10.1111/liv.13879
By:
- Addante, Annalisa;
- Roncero, Cesáreo;
- Almalé, Laura;
- Lazcanoiturburu, Nerea;
- García‐Álvaro, María;
- Fernández, Margarita;
- Sanz, Julián;
- Hammad, Seddik;
- Nwosu, Zeribe C.;
- Lee, Se‐Jin;
- Fabregat, Isabel;
- Dooley, Steven;
- ten Dijke, Peter;
- Herrera, Blanca;
- Sánchez, Aránzazu
Publication type:
Article
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages.
Published in:
Life Science Alliance, 2021, v. 4, n. 6, p. 1, doi. 10.26508/lsa.202000935
By:
- Kemp, Samantha B.;
- Steele, Nina G.;
- Carpenter, Eileen S.;
- Donahue, Katelyn L.;
- Bushnell, Grace G.;
- Morris, Aaron H.;
- The, Stephanie;
- Orbach, Sophia M.;
- Sirihorachai, Veerin R.;
- Nwosu, Zeribe C.;
- Espinoza, Carlos;
- Lima, Fatima;
- Brown, Kristee;
- Girgis, Alexander A.;
- Gunchick, Valerie;
- Yaqing Zhang;
- Lyssiotis, Costas A.;
- Franke, Timothy L.;
- Bednar, Filip;
- Rao, Arvind
Publication type:
Article
Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts.
Published in:
Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2016.00191
By:
- Nwosu, Zeribe C.;
- Alborzinia, Hamed;
- Wölfl, Stefan;
- Dooley, Steven;
- Yan Liu;
- Bahr, Matthias J.;
- Wing-Kin Syn
Publication type:
Article
Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.81289
By:
- Saab, Juan J. Apiz;
- Dzierozynski, Lindsey N.;
- Jonker, Patrick B.;
- Tabrizi, Roya Amini;
- Shah, Hardik;
- Menjivar, Rosa Elena;
- Scott, Andrew J.;
- Nwosu, Zeribe C.;
- Zhou Zhu;
- Chen, Riona N.;
- Oh, Moses;
- Sheehan, Colin;
- Wahl, Daniel R.;
- di Magliano, Marina Pasca;
- Lyssiotis, Costas A.;
- Macleod, Kay F.;
- Weber, Christopher R.;
- Muir, Alexander
Publication type:
Article
Arginase 1 is a key driver of immune suppression in pancreatic cancer.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.80721
By:
- Menjivar, Rosa E.;
- Nwosu, Zeribe C.;
- Wenting Du;
- Donahue, Katelyn L.;
- Hong, Hanna S.;
- Espinoza, Carlos;
- Brown, Kristee;
- Velez-Delgado, Ashley;
- Wei Yan;
- Lima, Fatima;
- Bischoff, Allison;
- Kadiyala, Padma;
- Salas-Escabillas, Daniel;
- Crawford, Howard C.;
- Bednar, Filip;
- Carpenter, Eileen;
- Yaqing Zhang;
- Halbrook, Christopher J.;
- Lyssiotis, Costas A.;
- di Magliano, Marina Pasca
Publication type:
Article
MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis.
Published in:
Archives of Toxicology, 2018, v. 92, n. 9, p. 2935, doi. 10.1007/s00204-018-2278-9
By:
- Tao, Le;
- Xue, Dongying;
- Shen, Dongxiao;
- Ma, Wenting;
- Zhang, Jie;
- Wang, Xuefei;
- Zhang, Wei;
- Wu, Liu;
- Pan, Kai;
- Yang, Yanqin;
- Nwosu, Zeribe C.;
- Dooley, Steven;
- Seki, Ekihiro;
- Liu, Cheng
Publication type:
Article
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52973-4
By:
- Mbah, Nneka E.;
- Myers, Amy L.;
- Sajjakulnukit, Peter;
- Chung, Chan;
- Thompson, Joyce K.;
- Hong, Hanna S.;
- Giza, Heather;
- Dang, Derek;
- Nwosu, Zeribe C.;
- Shan, Mengrou;
- Sweha, Stefan R.;
- Maydan, Daniella D.;
- Chen, Brandon;
- Zhang, Li;
- Magnuson, Brian;
- Zhu, Zirui;
- Radyk, Megan;
- Lavoie, Brooke;
- Yadav, Viveka Nand;
- Koo, Imhoi
Publication type:
Article
Combinatorial Gli activity directs immune infiltration and tumor growth in pancreatic cancer.
Published in:
PLoS Genetics, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.pgen.1010315
By:
- Scales, Michael K.;
- Velez-Delgado, Ashley;
- Steele, Nina G.;
- Schrader, Hannah E.;
- Stabnick, Anna M.;
- Yan, Wei;
- Mercado Soto, Nayanna M.;
- Nwosu, Zeribe C.;
- Johnson, Craig;
- Zhang, Yaqing;
- Salas-Escabillas, Daniel J.;
- Menjivar, Rosa E.;
- Maurer, H. Carlo;
- Crawford, Howard C.;
- Bednar, Filip;
- Olive, Kenneth P.;
- Pasca di Magliano, Marina;
- Allen, Benjamin L.
Publication type:
Article

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