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Exposure–Response Analysis of the Sodium–Glucose Cotransporter-2 Inhibitors Dapagliflozin and Empagliflozin on Kidney Hemodynamics in Patients with Type 2 Diabetes.
Published in:
Journal of Personalized Medicine, 2023, v. 13, n. 5, p. 747, doi. 10.3390/jpm13050747
By:
- van der Hoek, Sjoukje;
- Koomen, Jeroen V.;
- van Bommel, Erik J. M.;
- Mosterd, Charlotte M.;
- Scholtes, Rosalie A.;
- Hesp, Anne C.;
- Stevens, Jasper;
- van Raalte, Daniel H.;
- Heerspink, Hiddo J. L.
Publication type:
Article
Urinary Biomarkers in a Living Donor Kidney Transplantation Cohort—Predictive Value on Graft Function.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 6, p. 5649, doi. 10.3390/ijms24065649
By:
- Huisman, G. J. Julia;
- Spraakman, Nora A.;
- Koomen, Jeroen V.;
- Talsma, A. Marrit;
- Pol, Robert A.;
- Berger, Stefan P.;
- Leuvenink, Henri G. D.;
- Struys, Michel M. R. F.;
- Nieuwenhuijs-Moeke, Gertrude J.
Publication type:
Article
A Review of the Dose Justification of Phase 3 Trials to Regulatory Authorities for Drugs Intended for the Treatment of Type 2 Diabetes in Europe.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.626766
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Monster-Simons, Margje H.;
- Heerspink, Hiddo J. L.;
- Mol, Peter G. M.
Publication type:
Article
Inter‐individual variability in atrasentan exposure partly explains variability in kidney protection and fluid retention responses: A post hoc analysis of the SONAR trial.
Published in:
Diabetes, Obesity & Metabolism, 2021, v. 23, n. 2, p. 561, doi. 10.1111/dom.14252
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Bakris, George;
- Correa‐Rotter, Ricardo;
- Hou, Fan Fan;
- Kitzman, Dalane W.;
- Kohan, Donald;
- Makino, Hirofumi;
- McMurray, John J. V.;
- Parving, Hans‐Henrik;
- Perkovic, Vlado;
- Tobe, Sheldon W.;
- Zeeuw, Dick;
- Heerspink, Hiddo J. L.
Publication type:
Article
Exposure–response relationships for the sodium‐glucose co‐transporter‐2 inhibitor dapagliflozin with regard to renal risk markers.
Published in:
Diabetes, Obesity & Metabolism, 2020, v. 22, n. 6, p. 916, doi. 10.1111/dom.13976
By:
- Kroonen, Marjolein Y. A. M.;
- Koomen, Jeroen V.;
- Petrykiv, Sergei I.;
- Laverman, Gozewijn D.;
- Heerspink, Hiddo J. L.;
- Stevens, Jasper
Publication type:
Article
Exposure and response analysis of aleglitazar on cardiovascular risk markers and safety outcomes: An analysis of the AleCardio trial.
Published in:
Diabetes, Obesity & Metabolism, 2020, v. 22, n. 1, p. 30, doi. 10.1111/dom.13862
By:
- Koomen, Jeroen V.;
- Heerspink, Hiddo J. L.;
- Schrieks, Ilse C.;
- Schwartz, Gregory G.;
- Lincoff, A. Michael;
- Nicholls, Stephen J.;
- Svensson, Anders;
- Wedel, Hans;
- Weichert, Arlette;
- Grobbee, Diederick E.;
- Stevens, Jasper
Publication type:
Article
Determining the optimal dose of atrasentan by evaluating the exposure‐response relationships of albuminuria and bodyweight.
Published in:
Diabetes, Obesity & Metabolism, 2018, v. 20, n. 8, p. 2019, doi. 10.1111/dom.13312
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Mostafa, Nael M.;
- Parving, Hans‐Henrik;
- de Zeeuw, Dick;
- Heerspink, Hiddo J. L.
Publication type:
Article
Infliximab in paediatric inflammatory bowel disease: External evaluation of population pharmacokinetic models.
Published in:
British Journal of Clinical Pharmacology, 2024, v. 90, n. 9, p. 2200, doi. 10.1111/bcp.16126
By:
- Heikal, Omnia Salah;
- van Rheenen, Patrick F.;
- Touw, Daan J.;
- Kosterink, Jos G. W.;
- Maurer, Marina;
- Koomen, Jeroen V.;
- Chelle, Pierre;
- Mian, Paola
Publication type:
Article
Exposure–response relationships of dapagliflozin on cardiorenal risk markers and adverse events: A pooled analysis of 13 phase II/III trials.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 11, p. 2192, doi. 10.1111/bcp.14318
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Heerspink, Hiddo J.L.
Publication type:
Article
Organic Anion Transporter Gene Variants Associated With Plasma Exposure and Long‐Term Response to Atrasentan in Patients With Diabetic Kidney Disease.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 5, p. 1098, doi. 10.1002/cpt.2721
By:
- Smeijer, J. David;
- Koomen, Jeroen V.;
- Kohan, Donald E.;
- McMurray, John J. V.;
- Bakris, George L.;
- Correa‐Rotter, Ricardo;
- Hou, Fan‐Fan;
- Kitzman, Dalane W.;
- Makino, Hirofumi;
- Mayer, Gert;
- Nowicki, Michal;
- Perkovic, Vlado;
- Rossing, Peter;
- Tobe, Sheldon;
- Parving, Hans‐Henrik;
- de Zeeuw, Dick;
- Heerspink, Hiddo J. L.
Publication type:
Article
Individual Atrasentan Exposure is Associated With Long‐term Kidney and Heart Failure Outcomes in Patients With Type 2 Diabetes and Chronic Kidney Disease.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1631, doi. 10.1002/cpt.2143
By:
- Koomen, Jeroen V.;
- Stevens, Jasper;
- Bakris, George;
- Correa‐Rotter, Ricardo;
- Hou, Fan Fan;
- Kitzman, Dalane W.;
- Kohan, Donald E.;
- Makino, Hirofumi;
- McMurray, John J. V.;
- Parving, Hans‐Henrik;
- Perkovic, Vlado;
- Tobe, Sheldon W.;
- Zeeuw, Dick;
- Heerspink, Hiddo J. L.
Publication type:
Article
A Joint Pharmacokinetic Model for the Simultaneous Description of Plasma and Whole Blood Tacrolimus Concentrations in Kidney and Lung Transplant Recipients.
Published in:
Clinical Pharmacokinetics, 2023, v. 62, n. 8, p. 1117, doi. 10.1007/s40262-023-01259-x
By:
- Koomen, Jeroen V.;
- Knobbe, Tim J.;
- Zijp, Tanja R.;
- Kremer, Daan;
- Gan, C. Tji;
- Verschuuren, Erik A. M.;
- Bakker, Stephan J. L.;
- Touw, Daan J.;
- Colin, Pieter J.
Publication type:
Article
Optimising the Nadroparin Dose for Thromboprophylaxis During Hemodialysis by Developing a Population Pharmacodynamic Model Using Anti-Xa Levels.
Published in:
Clinical Pharmacokinetics, 2022, v. 61, n. 11, p. 1559, doi. 10.1007/s40262-022-01162-x
By:
- Jaspers, Tessa C. C.;
- Meijer, Charlotte E.;
- Vleming, Louis Jean;
- Franssen, Casper F. M.;
- Diepstraten, Jeroen;
- Lukens, Michael V.;
- van den Bemt, Patricia M. L. A.;
- Maat, Barbara;
- Khorsand, Nakisa;
- Touw, Daniël J.;
- Koomen, Jeroen V.
Publication type:
Article
Evaluation of the Pharmacokinetics and Exposure–Response Relationship of Dapagliflozin in Patients without Diabetes and with Chronic Kidney Disease.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 4, p. 517, doi. 10.1007/s40262-020-00956-1
By:
- van der Aart-van der Beek, Annemarie B.;
- Koomen, Jeroen V.;
- Dekkers, Claire C. J.;
- Barbour, Sean J.;
- Boulton, David W.;
- Gansevoort, Ron T.;
- Greasley, Peter J.;
- Abdul Gafor, Abdul Halim;
- Laverman, Gozewijn D.;
- Li, Qiang;
- Lim, Soo Kun;
- Stevens, Jasper;
- Vervloet, Marc G.;
- Singh, Sunita;
- Cattran, Daniel C.;
- Reich, Heather N.;
- Cherney, David Z. I.;
- Heerspink, Hiddo J. L.
Publication type:
Article
Peri-Operative Kinetics of Plasma Mitochondrial DNA Levels during Living Donor Kidney Transplantation.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13579, doi. 10.3390/ijms241713579
By:
- Kroneisl, Marie;
- Spraakman, Nora A.;
- Koomen, Jeroen V.;
- Hijazi, Zeinab;
- Hoogstra-Berends, Femke H.;
- Leuvenink, Henri G. D.;
- Struys, Michel M. R. F.;
- Henning, Rob H.;
- Nieuwenhuijs-Moeke, Gertrude J.
Publication type:
Article

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