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- Title
Pigmented skin patches without scleroderma as a predominant clinical symptom revealing systemic sclerosis.
- Authors
Darrigade, A. S.; Vedie, A. L.; Gauthier, C.; Cario‐André, M.; Taieb, A.; Truchetet, M. E.; Constans, J.; Seneschal, J.
- Abstract
Skin induration remains the major clinical symptom of systemic sclerosis ( SSc), an autoimmune disease with potentially life-threatening visceral involvement. However, skin induration can be absent in some patients, making the diagnosis difficult to confirm and leading to delay in management. Skin pigmentation abnormalities have been reported in patients with SSc, and can be important to recognize for diagnosis. We report two patients who developed hyperpigmented skin patches without any sign of scleroderma, as a major clinical skin symptom of incipient SSc.
- Subjects
HYPERPIGMENTATION; SYSTEMIC scleroderma; SKIN diseases; SKIN inflammation; AUTOIMMUNE diseases; SKIN biopsy; DIAGNOSIS; PATIENTS
- Publication
Clinical & Experimental Dermatology, 2016, Vol 41, Issue 4, p379
- ISSN
0307-6938
- Publication type
Article
- DOI
10.1111/ced.12752