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- Title
Association of Systolic BP to LVED Pressure Ratio with In-Hospital Mortality in STEMI Patients Undergoing PPCI.
- Authors
Arif, Zeeshan; Shahzad, Syed Khurram; Khan, Zahoor Aslam; Nadeem, Asif; Samore, Naseer Ahmed; Ahmed, Iftikhar; Siddiqui, Abdul Hameed
- Abstract
Objective: To determine the association of Systolic Blood Pressure to Left Ventricular End-Diastolic Pressure ratio with in-hospital mortality in ST-Elevation Myocardial Infarction patients undergoing Primary Percutaneous Coronary Intervention. Study Design: Analytical, cross-sectional study. Place and Duration of Study: Armed Forces Institute of Cardiology, National Institute of Heart Diseases, Rawalpindi Pakistan, from Apr-Jun 2023. Methodology: One hundred and ninety-eight patients who underwent Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction patients presenting within 12-hours were included using non-probability consecutive sampling technique. Patients were divided into two groups (Group-I= SBP/LVEDP ratio ≤4; Group-II= SBP/LVEDP ratio >4). SBP and LVEDP were measured during Primary Percutaneous Coronary Intervention. Demographic and clinical data, including risk factors and laboratory findings, were collected and SBP/LVEDP ratio was calculated. Study variables were compared among groups by applying independent t-test and Chi-square test. p-value<0.05 was kept as significant. Results: Among the study sample of 198, 126(63.6%) were males and females were 72(36.3%), mean age was 61.31±9.16 years. 21(10.6%) patients had SBP/LVEDP ratio≤4 (Group-I), while 177(89.3%) patients had SBP/LVEDP ratio>4 (Group-II). Group-I showed a higher prevalence of heart failure 5(23.8%), lower ejection fraction (35.48±7.56%), longer duration of in-hospital stay (8.76±2.48 days) (p<0.05), and higher TIMI scores (9.28±1.10) compared to Group-II. In-hospital mortality was also higher in Group-I (33.3%), compared to Group-II (6.2%) (p<0.05). Conclusion: The SBP/LVEDP ratio≤4 has significantly predicted increased risk of adverse outcomes and in-hospital mortality in STEMI patients who underwent Primary Percutaneous Coronary Intervention. This ratio may serve as a marker of compromised cardiac function and disease severity.
- Subjects
PAKISTAN; MYOCARDIAL infarction; HOSPITAL mortality; ST elevation myocardial infarction; PERCUTANEOUS coronary intervention; SYSTOLIC blood pressure; HEART diseases; VENTRICULAR ejection fraction
- Publication
Pakistan Armed Forces Medical Journal, 2024, Vol 74, pS17
- ISSN
0030-9648
- Publication type
Abstract
- DOI
10.51253/pafmj.v74isuppl-1.10896