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- Title
Predicting type 2 diabetes using Sasang constitutional medicine.
- Authors
Cho, Nam H; Kim, Jong Yeol; Kim, Sung Soo; Lee, Seung Ku; Shin, Chol
- Abstract
Aims/Introduction Sasang constitutional medicine ( SCM) has existed in traditional Korean medicine for more than 100 years. SCM consists of four different types: So-Eum ( SE), So-Yang ( SY), Tae-Eum ( TE) and Tae-Yang ( TY). It is of great importance that the Sasang constitution type ( SCT) be evaluated accurately and recognized by medical communities. Materials and Methods From the Ansung- Ansan prospective cohort study, 10,038 participants were recruited from the years 2001-2002. Of 10,038 original participants, 2,460 participants underwent SCT evaluation. The Cox proportional hazard model was used to predict diabetes during the 10-year follow-up period. Results During 10 years of follow up (22,007 person-years), 472 incidence cases (215/10,000 Incidence Density) of type 2 diabetes mellitus were documented. We identified that the TE group was significantly older, more obese, and had higher blood pressure, glucose metabolic values and lipid profiles levels. Relative risk ( RR) and 95% confident intervals ( CI) for type 2 diabetes were 1.696 (95% CI 1.204-2.39, P = 0.003) for TE when compared with the SE type. After controlling all potential confounders, the Cox proportional hazard model showed that RR was 1.635 (95% CI 1.111-2.406) in non-obese (body mass index <25) TE, and RR was 1.725 (95% CI 1.213-2.452) in obese (body mass index ≥25) TE when compared with the SE type. We did not find any differences when comparing SE and SY types. The findings shows that TE is a higher risk factor for type 2 Diabetes, independent of obesity level. Conclusions The present study suggests that the TE type, independent of obesity level, is a strong risk factor of type 2 diabetes.
- Subjects
TYPE 2 diabetes; PROPORTIONAL hazards models; RELATIVE medical risk; BODY mass index; OBESITY
- Publication
Journal of Diabetes Investigation, 2014, Vol 5, Issue 5, p525
- ISSN
2040-1116
- Publication type
Article
- DOI
10.1111/jdi.12189