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- Title
Ulcerative colitis associated with chronic granulomatous disease.
- Authors
Imanzade, Farid; Sayarri, Aliakbar; Tajik, Pantea
- Abstract
Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease which increases the body's susceptibility to infections caused by certain bacteria and fungi. CGD is a rare disease, caused by four genes, one type is 1X linked and the other three are “autosomal recessive”. Although clinical presentation is variable, but characteristic features are recurrent pneumonia, lymphadenitis, hepatic or other abscesses. Gastrointestinal tract symptoms are common in xlinked recessive form of CGD. These include gastric and esophageal obstruction and inflammatory bowel disease. GI involvement including small and large intestines, the findings of luminal narrowing and the presence of granuloma can make it difficult to distinguish from Crohn's disease. On the other hands according to the literature ulcerative colitis is rarely reported in patients with CGD. Our case presented with ulcerative colitis with CGD.
- Subjects
CROHN'S disease diagnosis; ULCERATIVE colitis diagnosis; ABDOMINAL pain; BIOPSY; BLOOD transfusion; BLOOD platelets; GASTROENTEROLOGY; HEMOGLOBINS; IMMUNITY; ULTRASONIC imaging
- Publication
Gastroenterology & Hepatology from Bed to Bench, 2015, Vol 8, Issue 3, p233
- ISSN
2008-2258
- Publication type
Article