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- Title
Peripheral retinal arteriolar leakage in giant cell arteritis: a case report.
- Authors
Ahmad, Meleha; Carey, Andrew R.; Eberhart, Charles G.; Siadati, Sepideh; Henderson, Amanda D.
- Abstract
A 76-year old African American female with a history of arteritic ischemic optic neuropathy (AION) secondary to biopsy-proven giant cell arteritis (GCA) presented with unilateral vision loss in her contralateral eye despite high-dose oral steroid treatment. Dilated fundus examination revealed three cotton wool spots. Fluorescein angiography showed slowed arteriolar filling with late staining of small peripheral arteries, consistent with small vessel arteritis. Laboratory tests for alternative vasculitides were negative. Review of her temporal artery biopsy specimen confirmed lymphoplasmacytic inflammation around small adventitial vessels with no destructive granulomatous or leukocytoclastic small vessel vasculitis, consistent with GCA. Our unique case demonstrates peripheral small vessel retinal arteriolar leakage in GCA, which is a rare finding. This association is of interest because GCA is commonly associated with medium to large vessel pathology without small vessel involvement.
- Subjects
FLUORESCENCE angiography; AFRICAN American history; GIANT cell arteritis; LEUKOCYTOCLASTIC vasculitis; TEMPORAL arteries; LEAKAGE; RETINAL blood vessels
- Publication
Journal of Ophthalmic Inflammation & Infection, 2021, Vol 11, Issue 1, p1
- ISSN
1869-5760
- Publication type
Article
- DOI
10.1186/s12348-021-00235-5