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- Title
Usage of Multimodal Evoked Potentials in Diagnosis of Central Nervous System Changes in Multiple Sclerosis.
- Authors
Özbek, Bahar; Balcı, Kemal; Çelik, Yahya
- Abstract
Objective: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing-remitting form of the disease. In this study, we aimed to examine the value of each evoked potential in demonstrating the demyelinating lesions in a homogeneous group of patients with relapsing-remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities. Patients and Methods: Twenty patients with relapsing-remitting multiple sclerosis, and 10 healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogeneous group. Visual, somatosensory and motor evoked potentials (VEP, SEP, MEP) were measured and the Expanded Disability Status Scale (EDSS) scores of the patients were calculated. Results: Of 20 patients, 15 (75%) had VEP abnormality, 14 (70%) had MEP abnormality and 12 (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. Abnormality of evoked potentials was also correlated with high EDSS scores. Conclusion: We concluded that evoked potentials, especially used in combination, are good markers to show nerve damage damage in patients with multiple sclerosis.
- Subjects
MULTIPLE sclerosis diagnosis; CENTRAL nervous system; COMPUTER software; EVOKED potentials (Electrophysiology); FISHER exact test; MEDICAL needs assessment; STATISTICS; U-statistics; DATA analysis; ACTIVITIES of daily living
- Publication
Turkish Journal of Neurology / Turk Noroloji Dergisi, 2011, Vol 17, Issue 1, p38
- ISSN
1301-062X
- Publication type
Article