The article outlines the research conducted by Nucleonics regarding scientific rationale and technology used in trail of its RNA interference, NUC B1000, a treatment for chronic Hepatitis B, in the U.S. It collaborated with Arkitek Studios wherein they use three dimensional (3D) animation for informed consent in a Phast I trial. They combined animation, voice over, stills and text to establish its finished product which can be viewed on its web site.