We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Predisposing factors for allogeneic blood transfusion in patients with ankylosing spondylitis undergoing primary unilateral total hip arthroplasty: a retrospective study.
- Authors
Bian, Tao; Zhang, Liang; Man, Siliang; Li, Hongchao; Dou, Yong; Zhou, Yixin
- Abstract
Background: The transfusion rate is relatively high in patients with ankylosing spondylitis (AS) undergoing total hip arthroplasty (THA). However, relevant studies focusing on the predisposing factors for transfusion with a large sample size are lacking. This study aimed to investigate the incidence of and risk factors for allogeneic blood transfusion in patients with AS undergoing primary unilateral THA. Methods: This retrospective study included 331 patients with AS who underwent primary unilateral THA between 2011 and 2021. Relevant parameters were collected through a chart review. Multivariate logistic regression analysis was conducted to identify possible factors associated with perioperative allogeneic blood transfusion. Results: A total of 113 (34.1%) patients received perioperative allogeneic blood transfusions. Factors related to receiving an allogeneic blood transfusion included prolonged operative duration (odds ratio [OR] per 10 min = 1.139, P = 0.047), increased estimated intraoperative blood loss (OR per 100 mL = 1.348, P < 0.001), and increased postoperative drainage volume (OR per 100 mL = 1.235, P = 0.024). A higher body mass index (BMI) (OR = 0.914, P = 0.012), perioperative tranexamic acid (TXA) use (OR = 0.166, P < 0.001), and a higher preoperative hemoglobin level (OR per 1 g/dL = 0.744, P = 0.004) decreased the risk of transfusion. Conclusions: In patients with AS undergoing THA, prolonged operative duration, increased estimated intraoperative blood loss, and increased postoperative drainage volume were found to be risk factors for transfusion, whereas a higher BMI, perioperative TXA use, and a higher preoperative hemoglobin level were protective factors. These results may aid in developing a better perioperative management strategy, ultimately reducing the need for transfusion.
- Subjects
CHINA; SURGICAL blood loss; PERIOPERATIVE care; C-reactive protein; TOTAL hip replacement; HEMOGLOBINS; CONFIDENCE intervals; ANKYLOSING spondylitis; BLOOD transfusion; MULTIPLE regression analysis; EVALUATION; SURGERY; PATIENTS; RETROSPECTIVE studies; DISEASE incidence; ACQUISITION of data; ANTICOAGULANTS; MANN Whitney U Test; FISHER exact test; RISK assessment; TRANEXAMIC acid; VENOUS thrombosis; T-test (Statistics); MEDICAL records; DISEASE duration; QUESTIONNAIRES; REGULATION of body fluids; DESCRIPTIVE statistics; CHI-squared test; ODDS ratio; BODY mass index; MEDICAL drainage; STATISTICAL models; DATA analysis software; DISEASE risk factors
- Publication
Journal of Orthopaedic Surgery & Research, 2023, Vol 18, Issue 1, p1
- ISSN
1749-799X
- Publication type
Article
- DOI
10.1186/s13018-022-03464-z