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- Title
Juego de reactivos para determinar tirotropina en suero por radioinmunoanálisis.
- Authors
Rodríguez Cabrera, M. E.; Blanca Fernández, S.; Baldor Navarro, F.; Mir Narbona, R.
- Abstract
The results of the validation of the set of reagents for thyrotrophin determination in human serum by a double antibody radioimmunoassay are presented. The kit provides eight vials including three controls sera which cover differents range of standard curve. The reference interval obtained for normal population (n = 150) was 0.9-4.4 mU/l. The replication of controls sera was 4.7; 6.3 and 8.5% and the reproductiveness of 8.8; 6.8 and 10.3% respectively. The assay sensitivity was 0.6 mU/l and the recovery of 94%. Paralellism between dose-response curves containing dilutions of a hypothyroid serum pool was found. The development and validation of this kit has allowed its satisfactorial application for diagnostic and clinical research.
- Subjects
BIOLOGICAL reagents; THYROTROPIN; SERUM; RADIOIMMUNOASSAY; ANTIGEN-antibody reactions; DIAGNOSIS; HYPERTHYROIDISM
- Publication
Nucleus, 1993, Issue 15, p13
- ISSN
0864-084X
- Publication type
Article