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- Title
The impact of JAK-STAT signaling on muscle regeneration.
- Authors
Doles, Jason D; Olwin, Bradley B
- Abstract
The article reports on a study by M. T. Tierney and colleagues which shows the role of Janus kinase-signal transducer and activator of transcription (JAK-STAT) signal transduction in muscle regeneration. It says that the findings provide an avenue for therapy development for age-related muscle wasting. It adds that the study also provide evidence supporting therapeutic interventions centered on satellite cells to attenuate loss of muscle function in age-related progressive muscle disorder.
- Subjects
MUSCLE regeneration; JANUS kinases; STAT proteins; CELLULAR signal transduction; WASTING syndrome; MUSCLE disease treatment; AGE factors in disease; TIERNEY, M. T.; THERAPEUTICS
- Publication
Nature Medicine, 2014, Vol 20, Issue 10, p1094
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm.3720