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- Title
Rare nature of mushroom poisoning means drug trials rarer still.
- Authors
Coombs, Amy
- Abstract
The article reports on the case of a woman and her two grandsons in California who were poisoned by eating the Amanita phalloides mushrooms. Due to the incident, it states that Todd Mitchell of Dominican Hospital persuaded the U.S. Food and Drug Administration (FDA) to approve an emergency investigational new drug (IND) application, which allowed the drug known as silibinin to be administered to the victims. Issues on silibinin's efficiency in treating mushroom poisoning are also discussed.
- Subjects
UNITED States; MUSHROOM poisoning; AMANITA phalloides; MITCHELL, Todd; POISONING; DRUG approval; DRUG efficacy; UNITED States. Food &; Drug Administration; THERAPEUTICS
- Publication
Nature Medicine, 2009, Vol 15, Issue 3, p225
- ISSN
1078-8956
- Publication type
Article
- DOI
10.1038/nm0309-225a