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- Title
Sinus Histiocytosis With Massive Lymphadenopathy (Rosai-Dorfman Disease) Involving the Ovary.
- Authors
Pelizzari, Giovanni; Bettini, Lamberto; Sleiman, Intissar; Spandrio, Sara; Balestrieri, Gian Paolo; Facchetti, Fabio
- Abstract
A 66-year-old woman affected by sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) is described. She presented with renal and ovarian masses. Percutaneous fine-needle aspiration was performed. Histologic specimens showed numerous histiocytes that contained lymphocytes or plasma cells in their cytoplasm. Strong reactivity for histiocyte-associated antigens was diffusely present in these cells. She was treated with prednisone and cyclophosphamide; a partial remission was obtained.
- Subjects
LYMPHATIC diseases; OVARIAN diseases; NEEDLE biopsy; MACROPHAGES; LYMPHOCYTES; PLASMA cells; CYTOPLASM; PREDNISONE
- Publication
International Journal of Surgical Pathology, 1995, Vol 2, Issue 4, p329
- ISSN
1066-8969
- Publication type
Article
- DOI
10.1177/106689699500200410